Lower genomic stability of induced pluripotent stem cells reflects increased non-homologous end joining

Cancer Communications

Table 1 Summary of sequencing results

Parameter	lv-iPSCs		ESCs		MEFs
Parameter	IR−	IR+	IR−	IR+	IR−	IR+
Total nucleotides sequenced (Gb)	64.1	71.5	72.0	70.9	64.7	70.1
Genome coverage (fold)	20×	21×	22×	23×	20×	21×
Total number of reads	634,852,868	708,065,514	765,056,092	754,255,820	640,447,936	693,376,402

ESCs mouse embryonic stem cells, IR ionizing radiation, lv-iPSCs lentivirus induced iPS cells, MEFs mouse embryonic fibroblasts

ISSN: 2523-3548