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Table 3 Five-year survival/failure rates and hazard ratios by age group for the 2492 Asian breast cancer patients treated with breast-conserving therapy (1989–2012)

From: Age exerts a continuous effect in the outcomes of Asian breast cancer patients treated with breast-conserving therapy

Clinical outcomes No. of events/no. of patients 5-year rate [% (95% CI)] Log-rank, P value Hazard ratio (95% CI) Cox model P value
Overall survival
 All patients 162/2492 95.7 (94.6–96.6)    
 ≤ 40 years at diagnosis 40/447 94.1 (90.6–96.4)   1.27 (0.88–1.82)  
 > 40 years at diagnosis 122/2045 96.1 (94.9–97.0) 0.198 1.00 0.209
Breast cancer-specific survival
 All patients 77/2492 98.0 (97.1–98.6)    
 ≤ 40 years at diagnosis 26/447 96.7 (93.7–98.3)   2.00 (1.23–3.23)  
 > 40 years at diagnosis 51/2045 98.3 (97.4–98.9) 0.004 1.00 0.007
Breast cancer-free interval
 All patients 277/2492 10.5 (9.0–12.1)    
 ≤ 40 years at diagnosis 85/447 15.3 (11.6–20.1)   1.92 (1.49–2.50)  
 > 40 years at diagnosis 192/2045 9.4 (7.9–11.1) < 0.001 1.00 < 0.001
Local recurrence
 All patients 89/2492 3.4 (2.6–4.4)    
 ≤ 40 years at diagnosis 31/447 5.2 (3.1–8.5)   2.33 (1.49–3.57)  
 > 40 years at diagnosis 58/2045 3.0 (2.2–4.1) < 0.001 1.00 < 0.001
  1. Proportional hazards assumption was violated for overall survival