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Fig. 4 | Cancer Communications

Fig. 4

From: NS1-binding protein radiosensitizes esophageal squamous cell carcinoma by transcriptionally suppressing c-Myc

Fig. 4

Silencing NS1-BP induces radioresistance of ESCC cells in vitro. a, b Depletion of NS1-BP decreased c-Myc expression and promoted proliferation of TE-1 cells. ce Loss-of-function studies revealed that NS1-BP depletion induced cellular radioresistance (c), and attenuated apoptosis (d) and unrepaired DNA damage (e) induced by irradiation (*P < 0.05, according to student’s t test)

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