Table 5 Hematologic and nonhematologic adverse events which ever occurred in 39 patients treated with FOLFIRINOX as a second-line treatment
Adverse event | Any grade | Grade 3 or more | ||
|---|---|---|---|---|
Number of patients | % | Number of patients | % | |
Hematologic | ||||
Neutropenia | 18 | 46.2 | 16 | 41.0 |
Thrombocytopenia | 7 | 17.9 | 1 | 2.6 |
Anemia | 23 | 59.0 | 3 | 7.7 |
Nonhematologic | ||||
Nausea | 23 | 59.0 | 4 | 10.3 |
Vomiting | 3 | 7.7 | 1 | 2.6 |
Diarrhea | 11 | 28.2 | 1 | 2.6 |
Fatigue | 9 | 23.1 | 2 | 5.1 |
Anorexia | 21 | 53.8 | 4 | 10.3 |
Constipation | 6 | 15.4 | ||
Mucositis | 12 | 30.8 | 3 | 7.7 |
Neuropathy | 5 | 12.8 | 1 | 2.6 |
Septic shock | 1a | 2.6 | ||
Pneumonia/pleural effusion | 2 | 5.1 | ||
Abdominal distension | 1 | 2.6 | ||
Alkaline phosphatase increased | 1 | 2.6 | ||
Hypokalemia | 1 | 2.6 | ||
Glossopharyngeal neuralgia | 1 | 2.6 | ||