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Fig. 2 | Cancer Communications

Fig. 2

From: Epidermal growth factor receptor (EGFR) T790M mutation identified in plasma indicates failure sites and predicts clinical prognosis in non-small cell lung cancer progression during first-generation tyrosine kinase inhibitor therapy: a prospective observational study

Fig. 2

EGFR mutations in ctDNA samples from patients with TKI resistance. a EGFR mutation profiles determined by ARMS. b EGFR mutation profiles in T790M+ and T790M− groups assessed by ARMS. c T790M mutation determined by ddPCR. d Scatter plot of the T790M abundance in the groups according to the T790M status by ARMS (top) and the number of patients with different abundance of T790M (bottom). TKI tyrosine kinase inhibitor, ctDNA circulating tumor DNA, EGFR epidermal growth factor receptor, ARMS amplification refractory mutation system, ddPCR droplet digital PCR

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