Table 1 Clinicopathologic characteristics of patients with colorectal oligometastasis to the liver after curative liver resection
Parameters | Total (n) | With ACT (n, %) | Without ACT (n, %) | P value |
|---|---|---|---|---|
Number of patients | 264 | 200 | 64 | Â |
Age, years | ||||
 ≤ 60 | 164 | 129 (64.5) | 35 (54.7) | 0.159 |
 > 60 | 100 | 71 (35.5) | 29 (45.3) |  |
Sex | ||||
 Male | 171 | 128 (64.0) | 43 (67.2) | 0.895 |
 Female | 93 | 72 (36.0) | 21 (32.8) |  |
Primary tumor location | ||||
 Colon | 163 | 126 (63.0) | 37 (57.8) | 0.457 |
 Rectum | 101 | 74 (37.0) | 27 (42.8) |  |
Primary tumor differentiation | ||||
 Well to moderate | 206 | 155 (77.5) | 51 (79.7) | 0.713 |
 Poor | 58 | 45 (22.5) | 13 (20.3) |  |
T stagea | ||||
 1–3 | 157 | 122 (65.2) | 35 (66.5) | 0.707 |
 4 | 86 | 65 (34.8) | 21 (33.5) |  |
N stageb | ||||
 0 | 103 | 78 (42.9) | 25 (45.3) | 0.814 |
 1–2 | 135 | 104 (57.1) | 31 (55.4) |  |
Timing of metastasis | ||||
 Synchronous | 171 | 136 (68.0) | 35 (54.7) | 0.052 |
 Metachronous | 93 | 64 (32.0) | 29 (45.3) |  |
Number of metastatic tumors | ||||
 1 | 140 | 102 (51.0) | 38 (59.4) | 0.501 |
 2–3 | 99 | 78 (39.0) | 21 (32.8) |  |
 4–5 | 25 | 20 (10.0) | 5 (7.8) |  |
Metastases diameter (cm)c | ||||
 ≤ 3 | 173 | 134 (68.0) | 39 (61.9) | 0.371 |
 > 3 | 87 | 63 (32.0) | 24 (38.1) |  |
Preoperative CEA (ng/mL)d | ||||
 ≤ 50 | 200 | 156 (81.7) | 44 (73.3) | 0.161 |
 > 50 | 51 | 35 (18.3) | 16 (26.7) |  |
Preoperative CA19-9 (U/mL)a | ||||
 ≤ 35 | 166 | 128 (68.8) | 38 (66.7) | 0.760 |
 > 35 | 77 | 58 (31.2) | 19 (33.3) |  |
Preoperative chemotherapy | ||||
 Yes | 122 | 98 (49.0) | 24 (37.5) | 0.108 |
 No | 142 | 102 (51.0) | 40 (62.5) |  |
MSKCC-CRSe | ||||
 0–2 | 162 | 127 (73.4) | 35 (67.3) | 0.390 |
 3–5 | 63 | 46 (26.6) | 17 (32.7) |  |