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Table 3 Radiation parameters, tumor responses and complications

From: Boron neutron capture therapy for vulvar melanoma and genital extramammary Paget’s disease with curative responses

Case Date at BNCT Irradiation period (min) Minimum tumor dose (Gy-Eq) Maximum skin/mucosa dose (Gy-Eq) Tumor response Complications Loco-regional control and clinical outcome
1 2005.11.9 49 29 8.0 CR Pain (Grade 2) CR: 1.1 years (death with pulmonary metastases)
2 2010.11.26 65 23 8.7 CR Erosion (Grade 2) CR: 6.9 years (alive with NED)
3 2011.2.10 78 18 7.3 CR Erosion (Grade 2) CR: 6.5 years (alive with NED)
4 2014.4.17 50 20 6.4 CR Mucositis (Grade 1) CR: 3.2 years (death due to heart disease)
  1. BNCT boron neutron capture therapy, CR complete response, NED no evidence of disease