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Table 3 Radiation parameters, tumor responses and complications

From: Boron neutron capture therapy for vulvar melanoma and genital extramammary Paget’s disease with curative responses

Case

Date at BNCT

Irradiation period (min)

Minimum tumor dose (Gy-Eq)

Maximum skin/mucosa dose (Gy-Eq)

Tumor response

Complications

Loco-regional control and clinical outcome

1

2005.11.9

49

29

8.0

CR

Pain (Grade 2)

CR: 1.1 years (death with pulmonary metastases)

2

2010.11.26

65

23

8.7

CR

Erosion (Grade 2)

CR: 6.9 years (alive with NED)

3

2011.2.10

78

18

7.3

CR

Erosion (Grade 2)

CR: 6.5 years (alive with NED)

4

2014.4.17

50

20

6.4

CR

Mucositis (Grade 1)

CR: 3.2 years (death due to heart disease)

  1. BNCT boron neutron capture therapy, CR complete response, NED no evidence of disease