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Table 4 Univariate and multivariate analysis of overall survival in all 1227 patients

From: Long- versus short-interval follow-up after resection of hepatocellular carcinoma: a retrospective cohort study

Variables

Univariate analysis

Multivariate analysis

Wald Chi square

P

HR

95% CI

P

Gender (male:female)

0.33

0.567

   

Age (year) (> 60: ≤ 60)

0.04

0.834

   

PLT ((109/L)) (≤ 100: > 100)

0.11

0.742

   

ALB (g/L) (≤ 35: > 35)

0.04

0.848

   

TBIL (μmol/L) (> 17.1: ≤ 17.1)

3.48

0.062

   

PT (s) (> 16: ≤ 16)

0

0.993

   

AFP (ng/mL) (> 200: ≤ 200)

0.53

0.468

   

Hepatitis (yes:no)

1.53

0.216

   

Cirrhosis (yes:no)

0.66

0.416

   

Tumor number (multiple:solitary)

18.8

< 0.001

2.058

1.386–3.057

< 0.001

Tumor size (cm) (> 5: ≤ 5)

14.4

< 0.001

1.584

1.079–2.325

0.019

MVI (yes: no)

8.1

0.006

1.703

1.301–1.965

0.008

Tumor differentiation (poor:others)

1.22

0.269

   

Tumor location (non-subcapsular:subcapsular)

2.79

0.095

   

Resection margin (cm) (≤ 1: > 1)

0.97

0.323

   

Hemorrhage (mL) (> 400: ≤ 400)

7.6

0.006

1.361

0.896–2.066

0.149

ALBI grade (II:I)

3.46

0.063

   

Follow-up interval (short:long)

1.03

0.311

   
  1. PLT platelet, ALB albumin, TBIL total bilirubin, PT prothrombin time, AFP alpha-fetoprotein, MVI microvascular invasion, ALBI albumin-bilirubin