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Table 4 Univariate and multivariate analysis of overall survival in all 1227 patients

From: Long- versus short-interval follow-up after resection of hepatocellular carcinoma: a retrospective cohort study

Variables Univariate analysis Multivariate analysis
Wald Chi square P HR 95% CI P
Gender (male:female) 0.33 0.567    
Age (year) (> 60: ≤ 60) 0.04 0.834    
PLT ((109/L)) (≤ 100: > 100) 0.11 0.742    
ALB (g/L) (≤ 35: > 35) 0.04 0.848    
TBIL (μmol/L) (> 17.1: ≤ 17.1) 3.48 0.062    
PT (s) (> 16: ≤ 16) 0 0.993    
AFP (ng/mL) (> 200: ≤ 200) 0.53 0.468    
Hepatitis (yes:no) 1.53 0.216    
Cirrhosis (yes:no) 0.66 0.416    
Tumor number (multiple:solitary) 18.8 < 0.001 2.058 1.386–3.057 < 0.001
Tumor size (cm) (> 5: ≤ 5) 14.4 < 0.001 1.584 1.079–2.325 0.019
MVI (yes: no) 8.1 0.006 1.703 1.301–1.965 0.008
Tumor differentiation (poor:others) 1.22 0.269    
Tumor location (non-subcapsular:subcapsular) 2.79 0.095    
Resection margin (cm) (≤ 1: > 1) 0.97 0.323    
Hemorrhage (mL) (> 400: ≤ 400) 7.6 0.006 1.361 0.896–2.066 0.149
ALBI grade (II:I) 3.46 0.063    
Follow-up interval (short:long) 1.03 0.311    
  1. PLT platelet, ALB albumin, TBIL total bilirubin, PT prothrombin time, AFP alpha-fetoprotein, MVI microvascular invasion, ALBI albumin-bilirubin