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Table 1 Baseline characteristics of 2126 patients who underwent resection for hepatocellular carcinoma stratified by risk of recurrence

From: Long- versus short-interval follow-up after resection of hepatocellular carcinoma: a retrospective cohort study

Characteristics Low-risk patients
(n = 1425) (%)
High-risk patients
(n = 701) (%)
P
Gender 0.509
 Male 1244 (87.3) 619 (88.3)  
 Female 181 (12.7) 82 (11.7)  
Age (years) 52 (17) 50 (18) 0.001
Tumor number < 0.001
 Solitary 137 (9.6) 293 (41.8)  
 Multiple 1288 (90.4) 408 (58.2)  
Tumor size (cm) < 0.001
 > 5 246 (17.3) 532 (75.9)  
 ≤ 5 1179 (82.7) 169 (24.1)  
 Tumor size (cm) 3.5 (2.2) 8 (4.8) < 0.001
Tumor location < 0.001
 Central 389 (27.3) 54 (7.7)  
 Subcapsular 1036 (72.7) 647 (92.3)  
Tumor differentiation 0.040
 Poor 194 (13.6) 119 (17)  
 Moderate and well 1231 (86.4) 582 (83)  
Tumor MVI < 0.001
 Yes 87 (6.1) 498 (71)  
 No 1338 (93.9) 203 (29)  
BCLC stage < 0.001
 0/A 1380 (96.8) 482 (68.8)  
 B 45 (3.2) 219 (31.2)  
Etiology 0.646
 Non-hepatitis 137 (9.6) 70 (10)  
 HBV 1267 (88.9) 624 (89)  
 HCV 21 (1.5) 7 (1)  
WBC (109/L) 5.8 (2.1) 6.3 (2.5) < 0.001
RBC (109/L) 4.75 (0.7) 4.8 (0.8) 0.010
Hemoglobin (g/L) 146.5 (17.5) 146 (21.0) 0.360
PLT (109/L) 161 (77) 189.5 (92) < 0.001
ALT (U/L) 35.7 (25.6) 38.4 (27.5) 0.002
AST (U/L) 31 (16.3) 39.6 (26.6) < 0.001
ALB (g/L) 43 (4.6) 42.3 (4.8) < 0.001
TBIL (μmol/L) 13.4 (6.6) 12.5 (6.2) 0.003
PT (s) 11.7 (1.3) 11.7 (1.3) 0.684
ALBI grade < 0.001
 I 1216 (85.3) 550 (78.5)  
 II 209 (14.7) 151 (21.5)  
AFP (ng/mL) < 0.001
 > 200 468 (32.8) 332 (47.4)  
 ≤ 200 957 (67.2) 369 (52.6)  
Cirrhosis 0.092
 Yes 1075 (75.4) 505 (72)  
 No 350 (24.6) 196 (28)  
Resection margin (cm) 1 (1.5) 1 (1.0) < 0.001
Operative blood loss (mL) < 0.001
 > 400 173 (12.1) 214 (30.5)  
 ≤ 400 1252 (87.9) 487 (69.5)  
  1. Values are presented as the median (interquartile range) or n (%)
  2. MVI microvascular invasion, BCLC stage Barcelona clinic liver cancer stage, HBV hepatitis B virus, HCV hepatitis C virus, WBC white blood cell, RBC red blood cell, PLT platelet, ALT alanine aminotransferase, AST aspartate aminotransferase, ALB albumin, TBIL total bilirubin, PT prothrombin time, ALBI albumin-bilirubin, AFP alpha-fetoprotein