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Table 4 Incidence of various clinical manifestations of cardiotoxicity in the patients

From: Cardiotoxicity of 5-fluorouracil and capecitabine in Chinese patients: a prospective study

Clinical manifestations All patients (n = 527) 5-fluorouracil (n = 196) Capecitabine (n = 331)
Heart failure 20 (3.8) 5 (2.6) 15 (4.5)
Myocardial infarction 6 (1.1) 2 (1.0) 4 (1.2)
Arrhythmia 110 (20.9) 33 (16.8) 77 (23.3)
 Sinus bradycardia 42 (8.0) 11 (5.6) 31 (9.1)
 Premature beat 33 (6.3) 10 (5.1) 23 (7.0)
 Conduction block 28 (5.3) 9 (4.6) 19 (5.7)
 Sinus tachycardia 26 (4.9) 11 (5.6) 15 (4.5)
 Atrial fibrillation 2 (0.4) 0 (0.0) 2 (0.6)
Ischemic change 105 (19.9) 39 (19.9) 66 (19.9)
 ST segment 70 (13.3) 23 (11.7) 47 (14.2)
 T segment 48 (9.1) 21 (10.7) 27 (8.2)
 P segment 9 (1.7) 3 (1.5) 6 (1.8)
 R segment 3 (0.6) 1 (0.5) 2 (0.6)
Total patients 161 (30.6) 49 (25.0) 112 (33.8)
  1. Data are represented as n (%)