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Table 1 Summary of 13 common core pathways associated with pancreatic cancer in six GEO microarray datasets

From: Integrative analysis of gene expression profiles reveals specific signaling pathways associated with pancreatic duct adenocarcinoma

Pathway ID Pathway name GSE71989 GSE15471 GSE16515 GSE32676 GSE41368 GSE28735 Total degree
Outd Ind Outd Ind Outd Ind Outd Ind Outd Ind Outd Ind
05200 Pathway in cancer 28 0 21 0 15 0 23 0 21 0 8 0 116
04115 P53 signaling pathway 2 16 2 12 2 6 1 13 1 11 0 3 69
04510 Focal adhesion 8 7 7 5 6 4 6 5 7 6 3 4 68
04060 Cytokine-cytokine receptor interaction 0 16 0 14 0 8 0 9 0 13 0 4 64
04810 Regulation of actin cytoskeleton 3 9 3 8 3 6 3 7 3 9 1 2 57
00010 Glycolysis/Gluconeogenesis 2 14 0 6 3 11 0 4 2 10 1 3 56
05322 Systemic lupus erythematosus 8 0 7 0 6 0 6 0 8 0 2 0 37
05219 Bladder cancer 6 1 5 1 5 1 5 1 4 1 1 1 32
05222 Small cell lung cancer 5 1 5 1 5 1 4 1 4 1 3 1 32
04610 Complement and coagulation cascades 1 7 0 6 0 2 0 2 1 6 0 1 26
04512 ECM-receptor interaction 1 3 1 3 1 3 1 3 1 3 1 3 24
04360 Axon guidance 3 0 3 0 3 0 3 0 3 0 2 0 17
05211 Renal cell carcinoma 4 1 2 1 1 1 2 1 2 1 0 1 17
  1. Outd outdegree, the number of downstream signaling pathways connected to the node signaling pathway; Ind indegree, the number of upstream signaling pathways connected to node signaling pathway; Total degree: outdegree + indegree