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Fig. 1 | Cancer Communications

Fig. 1

From: Amino acid transporter SLC7A11/xCT at the crossroads of regulating redox homeostasis and nutrient dependency of cancer

Fig. 1

Structure and transport function of system x −c . System x −c functions as a cystine/glutamate antiporter that imports one molecule of cystine in exchange for one molecule of intracellular glutamate. It is a heterodimer of the light chain subunit SLC7A11, which mediates transport activity of system x −c , and heavy chain subunit SLC3A2 that regulates trafficking of SLC7A11 to the plasma membrane

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Cancer Communications

ISSN: 2523-3548

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