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Fig. 3 | Cancer Communications

Fig. 3

From: Ultrasound-guided fine needle aspiration of retropharyngeal lymph nodes after radiotherapy for nasopharyngeal carcinoma: a novel technique for accurate diagnosis

Fig. 3

Representative case of a cancer-positive result in the retropharyngeal lymph node (RLN) confirmed during the first endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) sampling session (Patient #11). a T1-weighed contrast-enhanced magnetic resonance imaging (MRI) revealed an enlarged left RLN in a patient with nasopharyngeal carcinoma. b Pathologic examination indicated cancer-positive results after a single EUS-FNA sampling session. On biopsy, the tumor showed sheets of cells with a characteristic syncytial pattern of growth, large nuclei, coarse chromatin, and conspicuous nucleoli. c Cytologic examination results indicated cancer-positive results after a single EUS-FNA sampling session. Cytological smears showed cohesive clusters of uniform large tumor cells associated with lymphocytic infiltration. Round or oval vesicular nuclei with a syncytial appearance, conspicuous nucleoli, and finely granular cytoplasm were noted. d The patient exhibited a complete response after salvage radiotherapy. No tumor was noted on MRI. 1 = pre-treatment RLN; 2 = post-treatment RLN

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