Fig. 4From: Efficacy of the hypoxia-activated prodrug evofosfamide (TH-302) in nasopharyngeal carcinoma in vitro and in vivoWestern blot analysis of HIF-1α and γH2AX expression. HNE-1 cells were treated with evofosfamide for 24 h under hypoxia or normoxia and then harvested and lysed. Expression of HIF-1α and histone variant H2AX (γH2AX) was detected by western blot analysis with the indicated antibodiesBack to article page