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Fig. 3 | Cancer Communications

Fig. 3

From: Xenograft tumors derived from malignant pleural effusion of the patients with non-small-cell lung cancer as models to explore drug resistance

Fig. 3

Computed tomography (CT) scans and pathology for patient CTC15063EGFR L858R, T790M and the patient-derived xenograft tumors. CT chest scans of patient CTC15063EGFR L858R, T790M were recorded 4.5 years after undergoing surgical resection and subsequent adjuvant chemotherapy (navelbine plus cisplatin). a Disease recurrence was found in a CT scan as a right sub-pleural nodule on 2012-3-12; b disease progression 26 months after erlotinib treatment was visible in a CT scan as malignant pleural effusion on 2014-6-27; c CT reexamination after 2 months of osimertinib treatment showed stable disease on 2015-10-8. Pathology (H&E staining) of tumor biopsy from d patient CTC15063EGFR L858R, T790M and e a xenograft CTC15063EGFR L858R, T790M tumor after osimertinib treatment

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