Table 4 Maximum toxicity grade in patients treated with TPF versus PF after matching
Adverse event | PF group [cases (%)] | TPF group [cases (%)] | P value | ||
|---|---|---|---|---|---|
Grade 0–2 | Grade 3–4 | Grade 0–2 | Grade 3–4 | ||
Neutropenia | 207 (70.4) | 87 (29.6) | 176 (59.9) | 118 (40.1) | 0.009 |
Anemia | 275 (93.5) | 19 (6.5) | 286 (97.3) | 8 (2.7) | 0.047 |
Thrombocytopenia | 268 (91.2) | 26 (8.8) | 284 (96.6) | 10 (3.4) | 0.009 |
Liver injury | 291 (99.0) | 3 (1.0) | 292 (99.3) | 2 (0.7) | 1.000 |
Kidney injury | 294 (100) | 0 (0) | 294 (100) | 0 (0) | 1.000 |
Nausea/vomiting | 114 (38.8) | 180 (61.2) | 151 (51.4) | 143 (48.6) | 0.003 |
Any of the above | 109 (37.0) | 185 (63.0) | 83 (28.2) | 211 (71.8) | 0.028 |