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Table 1 Difference in patient characteristics between the TPF and PF groups in the observational and propensity-matched datasets

From: Effect of induction chemotherapy with cisplatin, fluorouracil, with or without taxane on locoregionally advanced nasopharyngeal carcinoma: a retrospective, propensity score-matched analysis

Characteristic

Observational dataset [cases (%)]

Propensity score-matched dataset [cases (%)]

TPF

PF

P

TPF

PF

P

Total

315 (25.1)

941 (74.9)

 

294 (50.0)

294 (50.0)

 

Number of DSS events

31 (9.8)

228 (24.2)

 

28 (9.5)

55 (18.7)

 

Gender

  

0.649

  

0.114

 Male

235 (74.6)

715 (76.0)

 

224 (76.2)

206 (70.1)

 

 Female

80 (25.4)

226 (24.0)

 

70 (23.8)

88 (29.9)

 

Age

  

0.147

  

0.740

 ≤ 45

172 (54.6)

558 (59.3)

 

162 (55.1)

167 (56.8)

 

 > 45

143 (45.4)

383 (40.7)

 

132 (44.9)

127 (43.2)

 

Histology

  

0.376

  

0.362

 I

0 (0)

3 (0.3)

 

0 (0)

2 (0.7)

 

 II

18 (5.7)

41 (4.4)

 

18 (6.1)

17 (5.8)

 

 III

297 (94.3)

897 (95.3)

 

276 (93.9)

275 (93.5)

 

T stage

  

0.192

  

0.485

 T1

13 (4.1)

22 (2.3)

 

9 (3.1)

4 (1.4)

 

 T2

36 (11.4)

126 (13.4)

 

32 (10.9)

28 (9.5)

 

 T3

157 (49.9)

436 (46.3)

 

153 (52.0)

162 (55.1)

 

 T4

109 (34.6)

357 (38.0)

 

100 (34.0)

100 (34.0)

 

N stage

  

0.364

  

0.377

 N0

25 (7.9)

103 (10.9)

 

25 (8.5)

33 (11.2)

 

 N1

93 (29.5)

276 (29.3)

 

85 (28.9)

89 (30.3)

 

 N2

141 (44.8)

420 (44.7)

 

133 (45.2)

134 (44.6)

 

 N3

56 (17.8)

142 (15.1)

 

51 (17.4)

38 (12.9)

 

Clinical stage

  

0.649

  

0.456

 III

165 (52.4)

478 (50.8)

 

157 (53.4)

167 (56.9)

 

 IV

150 (47.6)

463 (49.2)

 

137 (46.6)

127 (43.1)

 

KPS

  

0.837

  

0.176

 70–80

7 (2.2)

25 (2.7)

 

7 (2.4)

2 (0.7)

 

 ≥ 90

308 (97.8)

916 (97.3)

 

287 (97.6)

292 (99.3)

 

Smoking

  

0.086

  

0.144

 Yes

119 (37.8)

409 (43.5)

 

115 (39.1)

97 (33.0)

 

 No

196 (62.2)

532 (56.5)

 

179 (60.9)

197 (67.0)

 

BMI

  

0.638

  

0.602

 < 19

33 (10.5)

96 (10.2)

 

31 (10.6)

29 (9.9)

 

 19–24

200 (63.5)

574 (61.0)

 

185 (62.9)

176 (59.8)

 

 > 24

82 (26.0)

271 (28.8)

 

78 (26.5)

89 (30.3)

 

CDDP dose (mg/m2)

  

0.741

  

0.438

 < 200 

188 (59.7)

551 (58.6)

 

185 (62.9)

195 (66.3)

 

 ≥ 200 

127 (40.3)

390 (41.4)

 

109 (37.1)

99 (33.7)

 

Number of IC cycles

  

0.169

  

0.729

 < 2

54 (17.1)

131 (13.9)

 

46 (15.7)

42 (14.3)

 

 ≥ 2

261 (82.9)

810 (86.1)

 

248 (84.3)

252 (85.7)

 

Radiation technique

  

< 0.001

  

1.0

 IMRT

263 (83.5)

262 (27.9)

 

242 (82.3)

242 (82.3)

 

 2D-CRT

52 (16.5)

679 (72.1)

 

52 (17.7)

52 (17.7)

 
  1. TPF taxane, cisplatin and 5-fluorouracil, PF cisplatin and 5-fluorouracil, DSS disease-specific survival, KPS Karnofsky Performance Status, BMI body mass index, IMRT intensity-modulated radiotherapy, 2D-CRT two-dimensional radiotherapy