|
Variable
|
The GEO datasetsa
|
The experimental set
|
|---|
|
Number of patients
|
5-year OS rate (%)
|
P valueb
|
Number of patients
|
5-year OS rate (%)
|
P valueb
|
|---|
|
Total
|
119
| | |
105
| | |
|
Age (years)
|
|
≤ 59
|
89
|
48.31
|
0.03
|
63
|
58.73
|
0.69
|
|
> 59
|
90
|
33.33
|
42
|
54.76
|
|
Sex
|
|
Female
|
33
|
33.33
|
0.30
|
25
|
48.00
|
0.16
|
|
Male
|
146
|
42.47
|
80
|
60.00
|
|
Tumor location
|
|
Upper thorax
|
20
|
25.00
|
0.10
|
7
|
71.4
|
0.15
|
|
Middle thorax
|
97
|
40.21
|
54
|
61.11
|
|
Lower thorax
|
62
|
46.78
|
44
|
50.00
|
|
Histological grade
|
|
G1
|
49
|
28.57
|
0.02
|
15
|
60.00
|
0.16
|
|
G2
|
98
|
44.90
|
73
|
64.29
|
|
G3
|
32
|
46.88
|
17
|
47.06
|
|
Primary tumor
|
|
T1
|
12
|
41.67
|
0.04
|
21
|
71.42
|
0.03
|
|
T2
|
27
|
40.74
|
63
|
63.49
|
|
T3
|
110
|
44.55
|
21
|
31.58
|
|
T4
|
30
|
26.67
| | | |
|
Regional lymph nodes
|
|
N0
|
83
|
56.62
|
< 0.01
|
50
|
68.00
|
< 0.01
|
|
N1
|
62
|
27.41
|
32
|
56.25
|
|
N2
|
22
|
27.27
|
16
|
37.50
|
|
N3
|
12
|
25.00
|
7
|
28.50
|
|
pTNM stage
|
|
I
|
10
|
70.00
|
0.00
|
6
|
33.30
|
0.00
|
|
II
|
77
|
53.25
|
48
|
70.80
|
|
III
|
92
|
27.17
|
51
|
47.05
|
|
Adjuvant therapy
|
|
Unknown
|
45
|
64.44
| |
0
| | |
|
No
|
30
|
30.00
|
0.50
|
43
|
58.14
|
0.70
|
|
Yes
|
104
|
33.65
|
62
|
56.45
|
|
Radiotherapy
|
Unknown
| | |
18
|
48.83
|
0.11
|
|
Chemotherapy
|
Unknown
| | |
19
|
59.09
|
|
Radiotherapy + chemotherapy
|
Unknown
| | |
25
|
48.00
|
- OS overall survival
- aComprising the GSE52634 and GSE53622 datasets
- bLog-rank test was used
