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Fig. 6 | Cancer Communications

Fig. 6

From: EYA4 inhibits hepatocellular carcinoma growth and invasion by suppressing NF-κB-dependent RAP1 transactivation

Fig. 6

Clinical relevance of EYA4 expression for the IκBα/RAP1 axis in human HCC tissues. a, b Representative immunohistochemistry images (a) and bar graphs (b) showing the relevance of EYA4 expression on the phospho-IκBα-Ser32 and RAP1 expression levels in 67 clinical HCC specimens. c, d Western-blotting analyses (c) and correlation analyses (d) were used to examine whether the EYA4 protein levels are associated with the levels of phospho-IκBα-Ser32 and RAP1 in eight HCC samples. EYA4 eyes absent homolog 4, IκBα nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha, GAPDH glyceraldehyde 3-phosphate dehydrogenase, p-IκBα phosphorylated IκBα, RAP1 RAS-related protein 1

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