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Table 2 Univariate and multivariate cox regression analysis for overall survival in patients with ESCC

From: Impact of type 2 diabetes mellitus on short-term and long-term outcomes of patients with esophageal squamous cell cancer undergoing resection: a propensity score analysis

Characteristic Univariate analysis Multivariate analysis
HR 95% CI P value HR 95% CI P value
Age (years)
 ≤ 45 vs. 46–59 vs. ≥ 60 1.002 0.990–1.015 0.720
Sex
 Female vs. male 0.769 0.607–0.975 0.030 0.865 0.680–1.101 0.239
Smoking status
 Yes vs. no 1.176 0.944–1.465 0.149
Drinking status
 Yes vs. no 1.195 0.922–1.548 0.178
Weight loss rate
 0 vs. > 0% to ≤ 5.0% vs. > 5.0% to ≤ 10.0% vs. > 10.0% 1.168 1.047–1.302 0.005 1.118 1.000–1.251 0.060
BMI (kg/m2)
 < 18.5 vs. ≥ 18.5 to < 25.0 vs. ≥ 25.0 0.970 0.779–1.207 0.784
Tumor location
 Upper vs. middle vs. lower 0.932 0.767–1.134 0.483
Tumor grade
 G1 vs. G2 vs. G3 1.489 1.271–1.745 < 0.001 1.373 1.164–1.621 < 0.001
pT category
 T1 vs. T2 vs. T3 vs. T4 1.642 1.308–2.062 < 0.001 1.257 0.982–1.611 0.070
pN category
 N0 vs. N1 vs. N2 vs. N3 1.820 1.594–2.079 < 0.001 1.474 1.181–1.839 0.001
pTNM stage
 Stage I vs. stage II vs. stage III 2.270 1.832–2.813 < 0.001 1.237 0.872–1.754 0.233
Complications
 None vs. anastomotic leakage vs. pneumonia vs. others 1.118 0.961–1.299 0.148
T2DM
 With T2DM vs. without T2DM 0.896 0.719–1.116 0.326
  1. ESCC esophageal squamous cell carcinoma, BMI body mass index, T2DM type 2 diabetes mellitus, pT pathological tumor, pN pathological node, pTNM stage pathological tumor/node/metastasis, HR hazard ratio, 95% CI 95% confidence interval, no comparison