Long-term outcomes of endoscopic submucosal dissection for high-grade dysplasia and early-stage carcinoma in the colorectum

Cancer Communications

Table 5 The association between clinicopathological characteristics of 514 patients with 520 advanced colorectal neoplasia lesions and local recurrence after ESD

Variable	Total (number of patients/lesions)	Local recurrence (%)	P value
Age (years)
≤ 60	202	1 (0.5)	0.943
> 60	312	3 (1.0)
Sex
Male	291	4 (1.4)	0.136
Female	223	0 (0.0)
Tumor size (mm)
< 40	412	2 (0.5)	0.408
≥ 40	108	2 (1.9)
Tumor location
Rectum	328	1 (0.3)	0.287
Colon	192	3 (1.6)
Growth type
Polypoid + LST-NG	373	2 (0.5)	0.681
LST-G	147	2 (1.4)
Histology
HGD + Tis	461	4 (0.9)	1.000
T1a + T1b	59	0 (0.0)
Lymphovascular infiltration
Absence	515	4 (0.8)	1.000
Presence	5	0 (0.0)
Resection status
En bloc	491	2 (0.4)	0.005
Piecemeal	29	2 (6.9)
Resection method
Standard ESD	449	2 (0.4)	0.163
Hybrid ESD	71	2 (2.8)

ESD endoscopic submucosal dissection, LST laterally spreading tumor, LST-G granular LST, LST-NG non-granular LST, HGD high-grade dysplasia