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Table 5 The association between clinicopathological characteristics of 514 patients with 520 advanced colorectal neoplasia lesions and local recurrence after ESD

From: Long-term outcomes of endoscopic submucosal dissection for high-grade dysplasia and early-stage carcinoma in the colorectum

Variable Total (number of patients/lesions) Local recurrence (%) P value
Age (years)
 ≤ 60 202 1 (0.5) 0.943
 > 60 312 3 (1.0)  
Sex
 Male 291 4 (1.4) 0.136
 Female 223 0 (0.0)  
Tumor size (mm)
 < 40 412 2 (0.5) 0.408
 ≥ 40 108 2 (1.9)  
Tumor location
 Rectum 328 1 (0.3) 0.287
 Colon 192 3 (1.6)  
Growth type
 Polypoid + LST-NG 373 2 (0.5) 0.681
 LST-G 147 2 (1.4)  
Histology
 HGD + Tis 461 4 (0.9) 1.000
 T1a + T1b 59 0 (0.0)  
Lymphovascular infiltration
 Absence 515 4 (0.8) 1.000
 Presence 5 0 (0.0)  
Resection status
 En bloc 491 2 (0.4) 0.005
 Piecemeal 29 2 (6.9)  
Resection method
 Standard ESD 449 2 (0.4) 0.163
 Hybrid ESD 71 2 (2.8)  
  1. ESD endoscopic submucosal dissection, LST laterally spreading tumor, LST-G granular LST, LST-NG non-granular LST, HGD high-grade dysplasia