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Table 4 Univariate and multivariate logistic regression analyses on the association between clinicopathological characteristics of patients with advanced colorectal neoplasia and ESD-related complications

From: Long-term outcomes of endoscopic submucosal dissection for high-grade dysplasia and early-stage carcinoma in the colorectum

Variable Univariate analysis Multivariate analysis
OR (95% CI) P value OR (95% CI) P value
Age (years)
 ≤ 60 1.000   1.000  
 > 60 0.909 (0.341–2.423) 0.849 0.863 (0.316–2.357) 0.774
Sex
 Male 1.000   1.000  
 Female 0.951 (0.357–2.532) 0.920 0.984 (0.363–2.670) 0.975
Tumor size (mm)
 < 40 1.000   1.000  
 ≥ 40 1.549 (0.536–4.476) 0.607 1.769 (0.587–5.329) 0.311
Tumor location
 Rectum 1.000   1.000  
 Colon 3.961 (1.377–11.391) 0.006 4.212 (1.437–12.344) 0.009
Growth type
 Polypoid + LST-NG 1.000   1.000  
 LST-G 0.776 (0.250–2.415) 0.869 0.757 (0.236–2.427) 0.639
Histology
 HGD + Tis 1.000   1.000  
 T1a + T1b 0.886 (0.861–0.912) 0.280 0.000 (0.000) 0.997
Resection method
 Standard ESD 1.000   1.000  
 Hybrid ESD 0.806 (0.181–3.589) 0.777 0.556 (0.120–2.577) 0.453
  1. ESD endoscopic submucosal dissection, OR odds ratio, CI confidence interval, LST laterally spreading tumor, LST-G granular LST, LST-NG non-granular LST, HGD high-grade dysplasia