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Table 3 Univariate and multivariate logistic regression analyses on the associations between clinicopathological characteristics of patients with advanced colorectal neoplasia and piecemeal resection by ESD

From: Long-term outcomes of endoscopic submucosal dissection for high-grade dysplasia and early-stage carcinoma in the colorectum

Variable

Total (number of patients/lesions)

Univariate analysis

Multivariate analysis

OR (95% CI)

P value

OR (95% CI)

P value

Age (years)

 ≤ 60

238

1.000

 

1.000

 

 > 60

372

0.698 (0.355–1.372)

0.295

0.714 (0.347–1.469)

0.360

Sex

 Male

357

1.000

 

1.000

 

 Female

253

0.858 (0.430–1.710)

0.663

0.842 (0.408–1.739)

0.642

Tumor size (mm)

 < 40

483

1.000

 

1.000

 

 ≥ 40

133

1.238 (0.568–2.702)

0.590

1.032 (0.445–2.389)

0.942

Tumor location

 Rectum

364

1.000

 

1.000

 

 Colon

252

2.342 (1.182–4.639)

0.012

2.058 (0.997–4.248)

0.051

Growth type

 Polypoid + LST-NG

442

1.000

 

1.000

 

 LST-G

174

1.290 (0.630–2.641)

0.485

2.179 (0.981–4.840)

0.056

Histology

 HGD + Tis

489

1.000

 

1.000

 

 T1a + T1b

127

1.324 (0.497–3.527)

0.773

1.693 (0.588–4.870)

0.329

Resection method

 Standard ESD

529

1.000

 

1.000

 

 Hybrid ESD

87

7.406 (3.678–14.914)

< 0.001

8.123 (3.820–17.272)

< 0.001

  1. ESD endoscopic submucosal dissection, OR odds ratio, CI confidence interval, LST laterally spreading tumor, LST-G granular LST, LST-NG non-granular LST, HGD high-grade dysplasia