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Table 3 Univariate and multivariate logistic regression analyses on the associations between clinicopathological characteristics of patients with advanced colorectal neoplasia and piecemeal resection by ESD

From: Long-term outcomes of endoscopic submucosal dissection for high-grade dysplasia and early-stage carcinoma in the colorectum

Variable Total (number of patients/lesions) Univariate analysis Multivariate analysis
OR (95% CI) P value OR (95% CI) P value
Age (years)
 ≤ 60 238 1.000   1.000  
 > 60 372 0.698 (0.355–1.372) 0.295 0.714 (0.347–1.469) 0.360
Sex
 Male 357 1.000   1.000  
 Female 253 0.858 (0.430–1.710) 0.663 0.842 (0.408–1.739) 0.642
Tumor size (mm)
 < 40 483 1.000   1.000  
 ≥ 40 133 1.238 (0.568–2.702) 0.590 1.032 (0.445–2.389) 0.942
Tumor location
 Rectum 364 1.000   1.000  
 Colon 252 2.342 (1.182–4.639) 0.012 2.058 (0.997–4.248) 0.051
Growth type
 Polypoid + LST-NG 442 1.000   1.000  
 LST-G 174 1.290 (0.630–2.641) 0.485 2.179 (0.981–4.840) 0.056
Histology
 HGD + Tis 489 1.000   1.000  
 T1a + T1b 127 1.324 (0.497–3.527) 0.773 1.693 (0.588–4.870) 0.329
Resection method
 Standard ESD 529 1.000   1.000  
 Hybrid ESD 87 7.406 (3.678–14.914) < 0.001 8.123 (3.820–17.272) < 0.001
  1. ESD endoscopic submucosal dissection, OR odds ratio, CI confidence interval, LST laterally spreading tumor, LST-G granular LST, LST-NG non-granular LST, HGD high-grade dysplasia