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Table 2 Multivariable analysis for overall survival and lung cancer-specific survival of patients with stage I or II SCLC

From: Selection of candidates for surgery as local therapy among early-stage small cell lung cancer patients: a population-based analysis

Variable

Overall survival

Lung cancer-specific survival

Hazard ratio (95% CI)

P

Hazard ratio (95% CI)

P

Age, per year increase

1.031 (1.025, 1.036)

< 0.001

1.029 (1.023, 1.036)

< 0.001

Year of diagnosis, per year later

0.963 (0.943, 0.983)

< 0.001

0.958 (0.936, 0.980)

< 0.001

Race

 White

Reference

 

Reference

 

 Black

0.840 (0.687, 1.026)

0.087

0.855 (0.688, 1.063)

0.158

 Others

0.951 (0.715, 1.265)

0.730

0.967 (0.708, 1.320)

0.832

Sex

 Male

Reference

 

Reference

 

 Female

0.941 (0.847, 1.046)

0.262

0.965 (0.859, 1.084)

0.544

Laterality of tumor location

 Left lung

Reference

 

Reference

 

 Right lung

1.010 (0.908, 1.123)

0.860

1.039 (0.924, 1.168)

0.524

 Others

1.044 (0.518, 2.102)

0.905

0.793 (0.328, 1.918)

0.607

T category

 T1

Reference

 

Reference

 

 T2

1.237 (1.104, 1.387)

< 0.001

1.311 (1.155, 1.488)

< 0.001

 T3

1.418 (1.197, 1.680)

< 0.001

1.644 (1.371, 1.972)

< 0.001

N category

 N0

Reference

 

Reference

 

 N1

1.330 (1.171, 1.511)

< 0.001

1.410 (1.227, 1.621)

< 0.001

Treatment

 Surgery

Reference

 

Reference

 

 RT

1.256 (1.071, 1.475)

0.005

1.265 (1.055, 1.515)

0.011

 Surgery + RT

0.860 (0.660, 1.120)

0.263

0.947 (0.710, 1.264)

0.713

 No surgery or RT

2.964 (2.509, 3.502)

< 0.001

3.171 (2.631, 3.822)

< 0.001

  1. SCLC small cell lung cancer, CI confidence interval, RT radiotherapy