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Table 2 Multivariable analysis for overall survival and lung cancer-specific survival of patients with stage I or II SCLC

From: Selection of candidates for surgery as local therapy among early-stage small cell lung cancer patients: a population-based analysis

Variable Overall survival Lung cancer-specific survival
Hazard ratio (95% CI) P Hazard ratio (95% CI) P
Age, per year increase 1.031 (1.025, 1.036) < 0.001 1.029 (1.023, 1.036) < 0.001
Year of diagnosis, per year later 0.963 (0.943, 0.983) < 0.001 0.958 (0.936, 0.980) < 0.001
Race
 White Reference   Reference  
 Black 0.840 (0.687, 1.026) 0.087 0.855 (0.688, 1.063) 0.158
 Others 0.951 (0.715, 1.265) 0.730 0.967 (0.708, 1.320) 0.832
Sex
 Male Reference   Reference  
 Female 0.941 (0.847, 1.046) 0.262 0.965 (0.859, 1.084) 0.544
Laterality of tumor location
 Left lung Reference   Reference  
 Right lung 1.010 (0.908, 1.123) 0.860 1.039 (0.924, 1.168) 0.524
 Others 1.044 (0.518, 2.102) 0.905 0.793 (0.328, 1.918) 0.607
T category
 T1 Reference   Reference  
 T2 1.237 (1.104, 1.387) < 0.001 1.311 (1.155, 1.488) < 0.001
 T3 1.418 (1.197, 1.680) < 0.001 1.644 (1.371, 1.972) < 0.001
N category
 N0 Reference   Reference  
 N1 1.330 (1.171, 1.511) < 0.001 1.410 (1.227, 1.621) < 0.001
Treatment
 Surgery Reference   Reference  
 RT 1.256 (1.071, 1.475) 0.005 1.265 (1.055, 1.515) 0.011
 Surgery + RT 0.860 (0.660, 1.120) 0.263 0.947 (0.710, 1.264) 0.713
 No surgery or RT 2.964 (2.509, 3.502) < 0.001 3.171 (2.631, 3.822) < 0.001
  1. SCLC small cell lung cancer, CI confidence interval, RT radiotherapy