Selection of candidates for surgery as local therapy among early-stage small cell lung cancer patients: a population-based analysis

Table 2 Multivariable analysis for overall survival and lung cancer-specific survival of patients with stage I or II SCLC

Variable	Overall survival		Lung cancer-specific survival
Variable	Hazard ratio (95% CI)	P	Hazard ratio (95% CI)	P
Age, per year increase	1.031 (1.025, 1.036)	< 0.001	1.029 (1.023, 1.036)	< 0.001
Year of diagnosis, per year later	0.963 (0.943, 0.983)	< 0.001	0.958 (0.936, 0.980)	< 0.001
Race
White	Reference		Reference
Black	0.840 (0.687, 1.026)	0.087	0.855 (0.688, 1.063)	0.158
Others	0.951 (0.715, 1.265)	0.730	0.967 (0.708, 1.320)	0.832
Sex
Male	Reference		Reference
Female	0.941 (0.847, 1.046)	0.262	0.965 (0.859, 1.084)	0.544
Laterality of tumor location
Left lung	Reference		Reference
Right lung	1.010 (0.908, 1.123)	0.860	1.039 (0.924, 1.168)	0.524
Others	1.044 (0.518, 2.102)	0.905	0.793 (0.328, 1.918)	0.607
T category
T1	Reference		Reference
T2	1.237 (1.104, 1.387)	< 0.001	1.311 (1.155, 1.488)	< 0.001
T3	1.418 (1.197, 1.680)	< 0.001	1.644 (1.371, 1.972)	< 0.001
N category
N0	Reference		Reference
N1	1.330 (1.171, 1.511)	< 0.001	1.410 (1.227, 1.621)	< 0.001
Treatment
Surgery	Reference		Reference
RT	1.256 (1.071, 1.475)	0.005	1.265 (1.055, 1.515)	0.011
Surgery + RT	0.860 (0.660, 1.120)	0.263	0.947 (0.710, 1.264)	0.713
No surgery or RT	2.964 (2.509, 3.502)	< 0.001	3.171 (2.631, 3.822)	< 0.001

ISSN: 2523-3548