Table 2 Multivariable analysis for overall survival and lung cancer-specific survival of patients with stage I or II SCLC
Variable | Overall survival | Lung cancer-specific survival | ||
|---|---|---|---|---|
Hazard ratio (95% CI) | P | Hazard ratio (95% CI) | P | |
Age, per year increase | 1.031 (1.025, 1.036) | < 0.001 | 1.029 (1.023, 1.036) | < 0.001 |
Year of diagnosis, per year later | 0.963 (0.943, 0.983) | < 0.001 | 0.958 (0.936, 0.980) | < 0.001 |
Race | ||||
White | Reference | Reference | ||
Black | 0.840 (0.687, 1.026) | 0.087 | 0.855 (0.688, 1.063) | 0.158 |
Others | 0.951 (0.715, 1.265) | 0.730 | 0.967 (0.708, 1.320) | 0.832 |
Sex | ||||
Male | Reference | Reference | ||
Female | 0.941 (0.847, 1.046) | 0.262 | 0.965 (0.859, 1.084) | 0.544 |
Laterality of tumor location | ||||
Left lung | Reference | Reference | ||
Right lung | 1.010 (0.908, 1.123) | 0.860 | 1.039 (0.924, 1.168) | 0.524 |
Others | 1.044 (0.518, 2.102) | 0.905 | 0.793 (0.328, 1.918) | 0.607 |
T category | ||||
T1 | Reference | Reference | ||
T2 | 1.237 (1.104, 1.387) | < 0.001 | 1.311 (1.155, 1.488) | < 0.001 |
T3 | 1.418 (1.197, 1.680) | < 0.001 | 1.644 (1.371, 1.972) | < 0.001 |
N category | ||||
N0 | Reference | Reference | ||
N1 | 1.330 (1.171, 1.511) | < 0.001 | 1.410 (1.227, 1.621) | < 0.001 |
Treatment | ||||
Surgery | Reference | Reference | ||
RT | 1.256 (1.071, 1.475) | 0.005 | 1.265 (1.055, 1.515) | 0.011 |
Surgery + RT | 0.860 (0.660, 1.120) | 0.263 | 0.947 (0.710, 1.264) | 0.713 |
No surgery or RT | 2.964 (2.509, 3.502) | < 0.001 | 3.171 (2.631, 3.822) | < 0.001 |