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Table 2 Different clinicopathological characteristics in the recurrent group and the non-recurrent group of TNBC patients

From: Genetic polymorphisms of autophagy-related gene 5 (ATG5) rs473543 predict different disease-free survivals of triple-negative breast cancer patients receiving anthracycline- and/or taxane-based adjuvant chemotherapy

Characteristic Non-recurrent group [cases (%)] Recurrent group [cases (%)] P value
Total 235 81  
Age (years) 0.768
 ≤ 40 56 (23.8) 18 (6.7)  
 > 40 179 (76.2) 63 (77.8)  
Family history of breast cancer 0.396
 Yes 35 (14.9) 9 (11.1)  
 No 200 (85.1) 72 (88.9)  
T stage 0.199
 pT0–T1 121 (51.5) 35 (43.2)  
 pT2–T4 114 (48.5) 46 (56.8)  
Axillary lymph node status < 0.001
 Negative 163 (69.4) 36 (44.4)  
 Positive 72 (30.6) 45 (55.6)  
TNM stage < 0.001
 0–I 91 (38.7) 18 (22.2)  
 II–III 144 (61.3) 63 (77.8)  
Pathological type 0.407
 Invasive ductal carcinoma 217 (92.3) 77 (95.0)  
  Grade 1/2 75 (31.9) 34 (42.0)  
  Grade 3 131 (55.7) 33 (40.7)  
  Unknown 11 (4.7) 10 (12.3)  
 Others 18 (7.7) 4 (5.0)  
Vascular invasion 0.003
 Yes 26 (11.1) 20 (24.7)  
 No 209 (88.9) 61 (75.3)  
Adjuvant radiotherapy 0.429
 Yes 87 (37.0) 34 (42.0)  
 No 148 (63.0) 47 (58.0)  
ATG5 rs473543 genotype 0.024
 AA 46 (19.6) 14 (17.3)  
 GA 97 (41.3) 47 (58.0)  
 GG 92 (39.1) 20 (24.7)