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Table 2 Different clinicopathological characteristics in the recurrent group and the non-recurrent group of TNBC patients

From: Genetic polymorphisms of autophagy-related gene 5 (ATG5) rs473543 predict different disease-free survivals of triple-negative breast cancer patients receiving anthracycline- and/or taxane-based adjuvant chemotherapy

Characteristic

Non-recurrent group [cases (%)]

Recurrent group [cases (%)]

P value

Total

235

81

 

Age (years)

0.768

 ≤ 40

56 (23.8)

18 (6.7)

 

 > 40

179 (76.2)

63 (77.8)

 

Family history of breast cancer

0.396

 Yes

35 (14.9)

9 (11.1)

 

 No

200 (85.1)

72 (88.9)

 

T stage

0.199

 pT0–T1

121 (51.5)

35 (43.2)

 

 pT2–T4

114 (48.5)

46 (56.8)

 

Axillary lymph node status

< 0.001

 Negative

163 (69.4)

36 (44.4)

 

 Positive

72 (30.6)

45 (55.6)

 

TNM stage

< 0.001

 0–I

91 (38.7)

18 (22.2)

 

 II–III

144 (61.3)

63 (77.8)

 

Pathological type

0.407

 Invasive ductal carcinoma

217 (92.3)

77 (95.0)

 

  Grade 1/2

75 (31.9)

34 (42.0)

 

  Grade 3

131 (55.7)

33 (40.7)

 

  Unknown

11 (4.7)

10 (12.3)

 

 Others

18 (7.7)

4 (5.0)

 

Vascular invasion

0.003

 Yes

26 (11.1)

20 (24.7)

 

 No

209 (88.9)

61 (75.3)

 

Adjuvant radiotherapy

0.429

 Yes

87 (37.0)

34 (42.0)

 

 No

148 (63.0)

47 (58.0)

 

ATG5 rs473543 genotype

0.024

 AA

46 (19.6)

14 (17.3)

 

 GA

97 (41.3)

47 (58.0)

 

 GG

92 (39.1)

20 (24.7)