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Table 3 Metastatic rates of small cervical lymph nodes based on MRI and PET/CT findings stratified by N category

From: Significant value of 18F-FDG-PET/CT in diagnosing small cervical lymph node metastases in patients with nasopharyngeal carcinoma treated with intensity-modulated radiotherapy

MRI-based N category

Group A

Group B

Group C

Group D

Group E

P c

Totala

Metastatic lymph nodes (%)b

Totala

Metastatic lymph nodes (%)b

Totala

Metastatic lymph nodes (%)b

Totala

Metastatic lymph nodes (%)b

Totala

Metastatic lymph nodes (%)b

N0 category

 Level I

37

0 (0)

9

0 (0)

4

0 (0)

1

0 (0)

0

0 (0)

1.000

 Level II

75

0 (0)

47

0 (0)

37

4 (10.8)

17

7 (41.2)

7

6 (85.7)

< 0.001

 Level III/Va

16

0 (0)

8

1 (12.5)

1

0 (0)

2

1 (50.0)

1

1 (100.0)

0.036

 Level IV/Vb

6

0 (0)

3

0 (0)

1

0 (0)

0

0 (0)

0

0 (0)

1.000

 P c1

1.000

0.164

1.000

1.000

1.000

 

 P c2

1.000

0.190

1.000

0.812

1.000

 

N1 category

 Level I

115

0 (0)

41

0 (0)

21

0 (0)

7

1 (14.3)

2

2 (100.0)

< 0.001

 Level II

239

8 (3.3)

189

34 (18.0)

168

54 (32.1)

95

54 (56.8)

68

56 (82.4)

< 0.001

 Level III/Va

85

7 (8.2)

52

3 (5.8)

25

8 (32.0)

13

9 (69.2)

5

5 (100.0)

< 0.001

 Level IV/Vb

19

1 (5.3)

17

2 (11.8)

8

4 (50.0)

9

7 (77.8)

4

4 (100.0)

< 0.001

 P c1

0.008

< 0.001

0.001

0.045

0.746

 

 P c2

0.147

0.056

0.592

0.341

0.647

 

N2 category

 Level I

22

0 (0)

16

0 (0)

6

1 (16.7)

1

0 (0)

1

1 (100.0)

0.013

 Level II

66

6 (9.1)

67

8 (11.9)

44

17 (38.6)

35

21 (60.0)

27

21 (77.8)

< 0.001

 Level III/Va

54

1 (1.9)

20

4 (20.0)

18

8 (44.4)

10

7 (70.0)

2

2 (100.0)

< 0.001

 Level IV/Vb

8

1 (12.5)

4

0 (0)

2

0 (0)

3

3 (100.0)

1

1 (100.0)

0.007

 P c1

0.151

0.305

0.441

0.130

1.000

 

 P c2

0.135

0.593

0.623

0.074

1.000

 

N3 category

 Level I

23

0 (0)

4

0 (0)

3

1 (33.3)

1

1 (100.0)

0

0 (0)

0.013

 Level II

16

3 (18.8)

26

7 (26.9)

14

5 (35.7)

20

12 (60.0)

9

8 (88.9)

< 0.001

 Level III/Va

15

0 (0)

11

0 (0)

14

7 (50.0)

9

7 (77.8)

4

3 (75.0)

< 0.001

 Level IV/Vb

12

1 (8.3)

12

2 (16.7)

8

8 (100.0)

14

12 (85.7)

6

5 (83.3)

< 0.001

 P c1

0.038

0.232

0.006

0.380

1.000

 

 P c2

0.117

0.06

0.003

0.225

1.000

 
  1. MRI magnetic resonance imaging, PET/CT positron emission tomography/computed tomography
  2. aTotal number of small cervical lymph nodes based on MRI findings
  3. bMetastatic number of small cervical lymph nodes based on PET/CT findings
  4. c P values were calculated using the Chi square test or Fisher’s exact test if indicated; P c1 : Comparison between levels I, II, III/Va and IV/Vb; P c2 : Comparison between levels II, III/Va and IV/Vb
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Cancer Communications

ISSN: 2523-3548

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