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Table 3 Metastatic rates of small cervical lymph nodes based on MRI and PET/CT findings stratified by N category

From: Significant value of 18F-FDG-PET/CT in diagnosing small cervical lymph node metastases in patients with nasopharyngeal carcinoma treated with intensity-modulated radiotherapy

MRI-based N category Group A Group B Group C Group D Group E P c
Totala Metastatic lymph nodes (%)b Totala Metastatic lymph nodes (%)b Totala Metastatic lymph nodes (%)b Totala Metastatic lymph nodes (%)b Totala Metastatic lymph nodes (%)b
N0 category
 Level I 37 0 (0) 9 0 (0) 4 0 (0) 1 0 (0) 0 0 (0) 1.000
 Level II 75 0 (0) 47 0 (0) 37 4 (10.8) 17 7 (41.2) 7 6 (85.7) < 0.001
 Level III/Va 16 0 (0) 8 1 (12.5) 1 0 (0) 2 1 (50.0) 1 1 (100.0) 0.036
 Level IV/Vb 6 0 (0) 3 0 (0) 1 0 (0) 0 0 (0) 0 0 (0) 1.000
 P c1 1.000 0.164 1.000 1.000 1.000  
 P c2 1.000 0.190 1.000 0.812 1.000  
N1 category
 Level I 115 0 (0) 41 0 (0) 21 0 (0) 7 1 (14.3) 2 2 (100.0) < 0.001
 Level II 239 8 (3.3) 189 34 (18.0) 168 54 (32.1) 95 54 (56.8) 68 56 (82.4) < 0.001
 Level III/Va 85 7 (8.2) 52 3 (5.8) 25 8 (32.0) 13 9 (69.2) 5 5 (100.0) < 0.001
 Level IV/Vb 19 1 (5.3) 17 2 (11.8) 8 4 (50.0) 9 7 (77.8) 4 4 (100.0) < 0.001
 P c1 0.008 < 0.001 0.001 0.045 0.746  
 P c2 0.147 0.056 0.592 0.341 0.647  
N2 category
 Level I 22 0 (0) 16 0 (0) 6 1 (16.7) 1 0 (0) 1 1 (100.0) 0.013
 Level II 66 6 (9.1) 67 8 (11.9) 44 17 (38.6) 35 21 (60.0) 27 21 (77.8) < 0.001
 Level III/Va 54 1 (1.9) 20 4 (20.0) 18 8 (44.4) 10 7 (70.0) 2 2 (100.0) < 0.001
 Level IV/Vb 8 1 (12.5) 4 0 (0) 2 0 (0) 3 3 (100.0) 1 1 (100.0) 0.007
 P c1 0.151 0.305 0.441 0.130 1.000  
 P c2 0.135 0.593 0.623 0.074 1.000  
N3 category
 Level I 23 0 (0) 4 0 (0) 3 1 (33.3) 1 1 (100.0) 0 0 (0) 0.013
 Level II 16 3 (18.8) 26 7 (26.9) 14 5 (35.7) 20 12 (60.0) 9 8 (88.9) < 0.001
 Level III/Va 15 0 (0) 11 0 (0) 14 7 (50.0) 9 7 (77.8) 4 3 (75.0) < 0.001
 Level IV/Vb 12 1 (8.3) 12 2 (16.7) 8 8 (100.0) 14 12 (85.7) 6 5 (83.3) < 0.001
 P c1 0.038 0.232 0.006 0.380 1.000  
 P c2 0.117 0.06 0.003 0.225 1.000  
  1. MRI magnetic resonance imaging, PET/CT positron emission tomography/computed tomography
  2. aTotal number of small cervical lymph nodes based on MRI findings
  3. bMetastatic number of small cervical lymph nodes based on PET/CT findings
  4. c P values were calculated using the Chi square test or Fisher’s exact test if indicated; P c1 : Comparison between levels I, II, III/Va and IV/Vb; P c2 : Comparison between levels II, III/Va and IV/Vb