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Table 2 Univariate and multivariate analyses of prognostic factors for distant metastasis-free survival of patients with N1 nasopharyngeal carcinoma

From: Prognostic values of the integrated model incorporating the volume of metastatic regional cervical lymph node and pretreatment serum Epstein–Barr virus DNA copy number in predicting distant metastasis in patients with N1 nasopharyngeal carcinoma

Variable

Univariate analysis

Multivariate analysis

HR (95% CI)

P value

HR (95% CI)

P valuea

Age

1.29 (0.79–2.10)

0.314

1.17 (0.67–1.89)

0.571

Gender

0.64 (0.35–1.17)

0.148

0.75 (0.61–1.45)

0.795

T category

2.01 (1.05–3.84)

0.035

2.42 (0.69–2.92)

0.334

GTVnd

3.02 (1.84–4.97)

< 0.001

2.22 (1.29–3.82)

0.004

EBV DNA copy number

4.61 (2.60–8.15)

< 0.001

3.24 (1.97–5.61)

< 0.001

Treatment method

3.05 (0.73–12.81)

0.128

2.12 (0.67–7.87)

0.697

Prognostic model

5.23 (3.14–8.69)

< 0.001

4.17 (2.34–7.59)

< 0.001

  1. HR hazard ratio, CI confidence interval, GTVnd gross tumor volume of lymph nodes, EBV Epstein–Barr virus
  2. a P values are calculated using an adjusted Cox proportional hazards model