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Table 2 Univariate and multivariate analyses of prognostic factors for distant metastasis-free survival of patients with N1 nasopharyngeal carcinoma

From: Prognostic values of the integrated model incorporating the volume of metastatic regional cervical lymph node and pretreatment serum Epstein–Barr virus DNA copy number in predicting distant metastasis in patients with N1 nasopharyngeal carcinoma

Variable Univariate analysis Multivariate analysis
HR (95% CI) P value HR (95% CI) P valuea
Age 1.29 (0.79–2.10) 0.314 1.17 (0.67–1.89) 0.571
Gender 0.64 (0.35–1.17) 0.148 0.75 (0.61–1.45) 0.795
T category 2.01 (1.05–3.84) 0.035 2.42 (0.69–2.92) 0.334
GTVnd 3.02 (1.84–4.97) < 0.001 2.22 (1.29–3.82) 0.004
EBV DNA copy number 4.61 (2.60–8.15) < 0.001 3.24 (1.97–5.61) < 0.001
Treatment method 3.05 (0.73–12.81) 0.128 2.12 (0.67–7.87) 0.697
Prognostic model 5.23 (3.14–8.69) < 0.001 4.17 (2.34–7.59) < 0.001
  1. HR hazard ratio, CI confidence interval, GTVnd gross tumor volume of lymph nodes, EBV Epstein–Barr virus
  2. a P values are calculated using an adjusted Cox proportional hazards model