Table 1 Associations between serum EBV DNA copy number and GTVnd as well as clinical demographic characteristics of patients with N1 nasopharyngeal carcinoma
Characteristic | EBV DNA copy numbera | P value | |
|---|---|---|---|
≤ 4000 copies/mL (n = 477) | > 4000 copies/mL (n = 310) | ||
GTVnd (mL) | < 0.001 | ||
≤ 18.9 | 415 (87.0) | 223 (71.9) | |
> 18.9 | 62 (13.0) | 87 (28.1) | |
Gender | 0.142 | ||
Male | 336 (70.4) | 234 (75.5) | |
Female | 141 (29.6) | 76 (24.5) | |
Age (years) | 0.558 | ||
> 45 | 215 (45.1) | 147 (47.4) | |
≤ 45 | 262 (54.9) | 163 (52.6) | |
T category | < 0.001 | ||
T1–2 | 164 (34.4) | 57 (18.4) | |
T3–4 | 313 (65.6) | 253 (81.6) | |
Treatment method | < 0.001 | ||
Radiotherapy alone | 55 (11.5) | 14 (4.5) | |
CCRT | 280 (58.7) | 130 (41.9) | |
NACT + CCRT | 142 (29.8) | 166 (53.5) | |