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Table 3 Multivariate analyses of prognostic factors for 74 NSCLC patients with postoperative locoregional recurrence treated by radical radiotherapy

From: Survival and prognostic factors of non-small cell lung cancer patients with postoperative locoregional recurrence treated with radical radiotherapy

Variable OS PFS LRFS DMFS
HR (95% CI) P value HR (95% CI) P value HR (95% CI) P value HR (95% CI) P value
Recurrence site (stump vs. regional lymph nodes vs. ipsilateral lung vs. multiple sites)     1.421 (0.802–2.519) 0.229
BED of radiation (≥ 78 vs. < 78 Gy) 0.472 (0.070–3.182) 0.472   0.317 (0.112–0.899) 0.031  
EGFR status (wild-type vs. mutation type vs. unknown) 0.227 (0.034–1.498) 0.118    0.383 (0.171–0.855) 0.019
Radiation technique (3D-CRT vs. IMRT vs. SBRT) 4.406 (0.667–29.085) 0.124   1.525 (0.516–4.503) 0.445  
  1. OS overall survival, PFS progression free survival, LRFS local recurrence free survival, DMFS distant metastasis free survival, HR hazard ratio, CI confidence interval, BED biological effective dose, EGFR epidermal growth factor receptor, 3D-CRT 3-dimensional conformal radiotherapy, IMRT intensity-modulated radiotherapy, SBRT stereotactic body radiotherapy, GTV gross tumor volume, not included