Fig. 6
From: Systematic analyses of glutamine and glutamate metabolisms across different cancer types
Strong correlations between the level of change in reactive oxygen species (ROS) and the levels of change in glutamine and glutamate metabolisms across 11 types of cancer. ROS level is correlated with glutamine metabolism (r = 0.685, P = 0.020) (a) and glutamate metabolism (r = 0.655, P = 0.029) (b). In each panel, the X axis represents the difference between the expression levels of glutamine/glutamate metabolism in cancer versus control tissues, and the Y axis represents the difference between the ROS levels in cancer versus control tissues. BLCA, bladder urothelial carcinoma; BRCA, breast invasive carcinoma; COAD, colon adenocarcinoma; HNSC, head and neck squamous cell carcinoma; KICH, kidney chromophobe; KIRC, kidney renal clear cell carcinoma; KIRP, kidney renal papillary cell carcinoma; LIHC, liver hepatocellular carcinoma; LUAD, lung adenocarcinoma; PRAD, prostate adenocarcinoma; THCA, thyroid carcinoma