Fig. 1
From: Systematic analyses of glutamine and glutamate metabolisms across different cancer types
Differential expression of importer and synthase genes for a glutamine and b glutamate influx, and metabolisms of c glutamine and d glutamate in 11 types of cancer. BLCA, bladder urothelial carcinoma; BRCA, breast invasive carcinoma; COAD, colon adenocarcinoma; HNSC, head and neck squamous cell carcinoma; KICH, kidney chromophobe; KIRC, kidney renal clear cell carcinoma; KIRP, kidney renal papillary cell carcinoma; LIHC, liver hepatocellular carcinoma; LUAD, lung adenocarcinoma; PRAD, prostate adenocarcinoma; THCA, thyroid carcinoma; SLC1A5, solute carrier family 1 member 5; GLUL, glutamate–ammonia ligase; GLS, glutaminase; PFAS, phosphoribosylformylglycinamidine synthase; GMPS, guanine monophosphate synthase; CAD, carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; CTPS, CTP synthase 1; PPAT, phosphoribosyl pyrophosphate amidotransferase; OGDHL, oxoglutarate dehydrogenase-like; OGDH, oxoglutarate dehydrogenase; GFPT1, glutamine-fructose-6-phosphate transaminase 1; DSLT, dihydrolipoamide S-succinyltransferase; DCD, dermcidin; CS, citrate synthase; ASNS, asparagine synthetase; PSAT1, phosphoserine aminotransferase 1; GSS, glutathione synthetase; ALDH18A1, aldehyde dehydrogenase 18 family member A1