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Fig. 1 | Chinese Journal of Cancer

Fig. 1

From: Expression of voltage-gated sodium channel Nav1.5 in non-metastatic colon cancer and its associations with estrogen receptor (ER)-β expression and clinical outcomes

Fig. 1

Representative immunohistochemical (IHC) staining of voltage-gated sodium channel 1.5 (Nav1.5) protein in tissue microarray (TMA). a1, a2 colon adenocarcinoma with high Nav1.5 expression, with strong intensity and 100% malignant cells staining in the plasma membrane; b1, b2 colon adenocarcinoma with moderate Nav1.5 expression, with moderate intensity and 75% malignant cells staining in the cell membrane; c1, c2 colon adenocarcinoma with low Nav1.5 expression, with week intensity and 45% malignant cells staining in the cell membrane; d1, d2 high Nav1.5 expression in tumor-adjacent normal tissue, with strong intensity and 100% epithelial cells staining in the plasma membrane; e1, e2 moderate Nav1.5 expression in tumor-adjacent normal tissue, with moderate intensity and 80% epithelial cells staining in the cell membrane; f1, f2 negative Nav1.5 expression in tumor-adjacent normal tissue

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