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Table 1 Baseline characteristics of patients with unresectable hepatocellular carcinoma who underwent either HAIC or TACE

From: Hepatic artery infusion chemotherapy using mFOLFOX versus transarterial chemoembolization for massive unresectable hepatocellular carcinoma: a prospective non-randomized study

Variable

HAIC [cases (%)]

TACE [cases (%)]

P

Total

38

41

 

Age (years)

0.638

 ≤ 60

27 (71.1)

27 (65.9)

 

 > 60

11 (28.9)

14 (34.1)

 

Gender

0.215

 Male

30 (78.9)

37 (90.2)

 

 Female

8 (21.1)

4 (9.8)

 

Tumor size (cm)

1.000

 < 10

12 (31.6)

12 (29.3)

 

 ≥ 10

26 (68.4)

29 (70.7)

 

Tumor number

0.654

 ≤ 3

18 (47.4)

17 (41.5)

 

 > 3

20 (52.6)

24 (58.5)

 

BCLC stage

0.338

 A

15 (39.5)

11 (26.8)

 

 B

23 (60.5)

30 (73.2)

 

Liver cirrhosis

0.368

 No

20 (52.6)

26 (63.4)

 

 Yes

18 (47.4)

15 (36.6)

 

Neutrophil: lymphocyte ratio

0.361

 ≤ 3

22 (57.9)

28 (68.3)

 

 > 3

16 (42.1)

13 (31.7)

 

Hemoglobin (g/L)

1.000

 < 100

1 (2.6)

1 (2.4)

 

 ≥ 100

37 (97.4)

40 (97.6)

 

Platelet count

1.000

 < 100 × 109/L

1 (2.6)

2 (4.9)

 

 ≥ 100 × 109/L

37 (97.4)

39 (95.1)

 

Hepatitis B surface antigen

0.434

 Negative

2 (5.3)

5 (12.2)

 

 Positive

36 (94.7)

36 (87.8)

 

HBV DNA (IU/mL)

0.593

 ≤ 1000

10 (26.3)

8 (19.5)

 

 > 1000

28 (73.7)

33 (80.5)

 

PT (s)

0.003

 ≤ 13.5

28 (73.7)

40 (97.6)

 

 > 13.5

10 (26.3)

1 (2.4)

 

ALT (U/L)

1.000

 ≤ 40

17 (44.7)

18 (43.9)

 

 > 40

21 (55.3)

23 (56.1)

 

ALB (g/L)

0.655

 ≤ 40

20 (52.6)

19 (46.3)

 

 > 40

18 (47.4)

22 (53.7)

 

TBIL (μmol/L)

0.284

 ≤ 20.5

27 (71.1)

34 (82.9)

 

 > 20.5

11 (28.9)

7 (17.1)

 

AFP (ng/mL)

0.813

 ≤ 400

12 (31.6)

15 (36.6)

 

 > 400

26 (68.4)

26 (63.4)

 
  1. HAIC hepatic artery infusion chemotherapy; TACE transarterial chemoembolization; BCLC Barcelona Clinic Liver Cancer; HBV hepatitis B virus; PT prothrombin time; ALT alanine transaminase; ALB albumin; TBIL total bilirubin; AFP alpha-fetoprotein
  2. P values were calculated using a two-sided Chi square test