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Table 1 Characteristics of breast cancer patients by stage at diagnosis

From: The influence of stage at diagnosis and molecular subtype on breast cancer patient survival: a hospital-based multi-center study

Characteristic Overall Stage P valueb
I II III IV Unknowna
Total 4640 1334 2180 573 100 453  
Age (years) 52.9 ± 11.3 53.1 ± 11.5 52.9 ± 11.3 52.6 ± 11.0 53.3 ± 11.0 55.7 ± 13.6 0.85
BMI 25.0 ± 3.8 24.5 ± 3.6 25.2 ± 3.9 25.5 ± 4.0 25.0 ± 3.5 25.2 ± 3.9 < 0.01
Menopausal status 0.03
 Premenopausal 2017 (43.5) 616 (46.2) 956 (43.9) 244 (42.6) 36 (36.0) 165 (36.4)  
 Postmenopausal 2510 (54.1) 691 (51.8) 1175 (53.9) 318 (55.5) 62 (62.0) 264 (58.3)  
 Unknowna 113 (2.4) 27 (2.0) 49 (2.2) 11 (1.9) 2 (2.0) 24 (5.3)  
Histological grade < 0.01
 Well differentiated 349 (7.5) 147 (11.0) 136 (6.2) 20 (3.5) 5 (5.0) 41 (9.1)  
 Moderately differentiated 2549 (54.9) 714 (53.5) 1257 (57.7) 311 (54.3) 48 (48.0) 219 (48.3)  
 Poorly differentiated 899 (19.4) 224 (16.8) 461 (21.1) 140 (24.4) 15 (15.0) 59 (13.0)  
 Unknowna 843 (18.2) 249 (18.7) 326 (15.0) 102 (17.8) 32 (32.0) 134 (29.6)  
Histological type 0.28
 Ductal 4031 (86.9) 1161 (87.0) 1928 (88.4) 509 (88.8) 88 (88.0) 345 (76.2)  
 Lobular 149 (3.2) 43 (3.2) 60 (2.8) 23 (4.0) 3 (3.0) 20 (4.4)  
 Others 460 (9.9) 130 (9.8) 192 (8.8) 41 (7.2) 9 (9.0) 88 (19.4)  
Molecular subtype < 0.01
 Luminal A 2387 (51.4) 775 (58.1) 1122 (51.5) 267 (46.6) 32 (32.0) 191 (42.2)  
 Luminal B 535 (11.5) 144 (10.8) 246 (11.3) 72 (12.6) 18 (18.0) 55 (12.1)  
 HER2 365 (8.0) 78 (5.9) 178 (8.2) 67 (11.7) 11 (11.0) 31 (6.9)  
 Triple-negative 517 (11.1) 130 (9.7) 241 (11.1) 81 (14.1) 10 (10.0) 55 (12.1)  
 Unknowna 836 (18.0) 207 (15.5) 393 (18.0) 86 (15.0) 29 (29.0) 121 (26.7)  
  1. Continuous data are expressed as mean ± standard deviation (SD). Categorical data are expressed as number of cases (percent)
  2. aUnknown data were not included in the statistical tests
  3. b P values were calculated using one-way analysis of variance (ANOVA) test (continuous variables) and Chi square or exact test (categorical variables)