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Table 5 Clinicopathologic characteristics of 4 mCRC patients with rare BRAF mutations

From: Clinicopathologic features and treatment efficacy of Chinese patients with BRAF-mutated metastatic colorectal cancer: a retrospective observational study

Patient Gender BRAF mutation Age (years) TNM stage Differentiation Mucinous components Peritoneal metastases Distant lymph node metastasis
Patient 1 Female T599_V600insAGA 63 T4aN1cM1 Moderate No Yes Yes
Patient 2 Female K601E 65 T4N2M1 Moderate Yes Yes Yes
Patient 3 Male K601E 42 T4N2M1 Poor Yes Yes Yes
Patient 4 Female D594G 55 T3N2M1 Moderate No No No
  1. All of the 4 patients harboring rare BRAF mutations were identified with right-sided tumors and showed liver metastases
  2. None of the 4 patients showed lung metastases