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Table 5 Clinicopathologic characteristics of 4 mCRC patients with rare BRAF mutations

From: Clinicopathologic features and treatment efficacy of Chinese patients with BRAF-mutated metastatic colorectal cancer: a retrospective observational study

Patient

Gender

BRAF mutation

Age (years)

TNM stage

Differentiation

Mucinous components

Peritoneal metastases

Distant lymph node metastasis

Patient 1

Female

T599_V600insAGA

63

T4aN1cM1

Moderate

No

Yes

Yes

Patient 2

Female

K601E

65

T4N2M1

Moderate

Yes

Yes

Yes

Patient 3

Male

K601E

42

T4N2M1

Poor

Yes

Yes

Yes

Patient 4

Female

D594G

55

T3N2M1

Moderate

No

No

No

  1. All of the 4 patients harboring rare BRAF mutations were identified with right-sided tumors and showed liver metastases
  2. None of the 4 patients showed lung metastases