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Table 2 Univariate analysis of the prognostic values of clinicopathologic characteristics and protein expression in sporadic MPNST patients

From: The prognostic value of C-X-C motif chemokine receptor 4 in patients with sporadic malignant peripheral nerve sheath tumors

Parameter

Disease-free survival

Overall survival

HR

95% CI

P

HR

95% CI

P

Gender

0.791

0.409–1.530

0.486

1.203

0.585–2.472

0.616

Age group

1.003

0.508–1.983

0.992

0.628

0.280–1.407

0.258

Tumor site

1.606

1.004–2.571

0.048

0.882

0.540–1.440

0.615

Tumor size

1.199

0.792–1.814

0.391

0.972

0.610–1.548

0.905

AJCC stage

1.465

1.028–2.086

0.034

1.265

0.857–1.867

0.236

Radiotherapy

0.526

0.264–1.044

0.066

0.754

0.356–1.598

0.461

Chemotherapy

0.778

0.386–1.568

0.483

0.627

0.297–1.324

0.221

Surgical type

1.323

0.672–2.604

0.419

1.347

0.624–2.909

0.449

Recurrence

0.051

0.015–0.174

< 0.001

0.324

0.139–0.755

0.009

Metastasis

0.295

0.150–0.580

< 0.001

0.388

0.191–0.789

0.009

CXCR4

1.586

0.762–3.303

0.218

2.472

1.057–5.782

0.037

CXCL12

1.200

0.624–2.308

0.584

1.854

0.910–3.779

0.089

Cyclin D1

1.071

0.515–2.226

0.854

1.610

0.652–3.972

0.302

  1. Italic values indicate statistically significant difference
  2. MPNST malignant peripheral nerve sheath tumor, AJCC American Joint Committee on Cancer, CXCR4 C-X-C motif chemokine receptor 4, CXCL12 C-X-C motif chemokine ligand 12, HR hazard ratio, CI confidence interval
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Cancer Communications

ISSN: 2523-3548

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