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Table 2 Univariate analysis of the prognostic values of clinicopathologic characteristics and protein expression in sporadic MPNST patients

From: The prognostic value of C-X-C motif chemokine receptor 4 in patients with sporadic malignant peripheral nerve sheath tumors

Parameter Disease-free survival Overall survival
HR 95% CI P HR 95% CI P
Gender 0.791 0.409–1.530 0.486 1.203 0.585–2.472 0.616
Age group 1.003 0.508–1.983 0.992 0.628 0.280–1.407 0.258
Tumor site 1.606 1.004–2.571 0.048 0.882 0.540–1.440 0.615
Tumor size 1.199 0.792–1.814 0.391 0.972 0.610–1.548 0.905
AJCC stage 1.465 1.028–2.086 0.034 1.265 0.857–1.867 0.236
Radiotherapy 0.526 0.264–1.044 0.066 0.754 0.356–1.598 0.461
Chemotherapy 0.778 0.386–1.568 0.483 0.627 0.297–1.324 0.221
Surgical type 1.323 0.672–2.604 0.419 1.347 0.624–2.909 0.449
Recurrence 0.051 0.015–0.174 < 0.001 0.324 0.139–0.755 0.009
Metastasis 0.295 0.150–0.580 < 0.001 0.388 0.191–0.789 0.009
CXCR4 1.586 0.762–3.303 0.218 2.472 1.057–5.782 0.037
CXCL12 1.200 0.624–2.308 0.584 1.854 0.910–3.779 0.089
Cyclin D1 1.071 0.515–2.226 0.854 1.610 0.652–3.972 0.302
  1. Italic values indicate statistically significant difference
  2. MPNST malignant peripheral nerve sheath tumor, AJCC American Joint Committee on Cancer, CXCR4 C-X-C motif chemokine receptor 4, CXCL12 C-X-C motif chemokine ligand 12, HR hazard ratio, CI confidence interval