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Table 3 Univariate and multivariate analyses of clinicopathologic factors and SII for OS of patients with gastric cancer

From: Prognostic value of systemic immune-inflammation index in patients with gastric cancer

Variable

Univariate analysis

Multivariate analysis

HR (95% CI)

P value

HR (95% CI)

P value

Sex

0.904 (0.707–1.155)

0.420

 

NI

Age

1.301 (1.027–1.647)

0.029

1.356 (1.059–1.735)

0.026

Tumor location

0.766 (0.672–0.873)

<0.001

0.874 (0.762–1.003)

0.056

Tumor size

2.421 (1.897–3.092)

<0.001

1.290 (0.997–1.670)

0.017

Pathologic type

0.984 (0.886–1.092)

0.758

 

NI

Borrmann classification

1.790 (1.524–2.103)

<0.001

1.521 (1.279–1.810)

<0.001

TNM stage

2.428 (2.087–2.825)

<0.001

2.081 (1.772–2.443)

<0.001

CEA

1.844 (1.303–2.609)

0.001

1.431 (1.006–2.035)

0.027

NLR

1.581 (1.250–2.001)

<0.001

0.902 (0.637–1.278)

0.563

PLR

1.738 (1.332–2.267)

<0.001

1.272 (0.902–1.794)

0.170

SII

1.848 (1.455–2.348)

<0.001

1.551 (1.211–1.987)

0.015

  1. HR, hazard ratio; NI, not included; OS, overall survival; CI, confidence interval; CEA, carcinoembryonic antigen; NLR, neutrophil–lymphocyte ratio; PLR, platelet–lymphocyte ratio; SII, systemic immune-inflammation index