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Table 3 Subgroup analysis of medical expenditures for esophageal cancer diagnosis and treatment per patient

From: Medical expenditure for esophageal cancer in China: a 10-year multicenter retrospective survey (2002–2011)

Variable Expenditure per patient during 2002–2011 (CNY) Statisticsa P Expenditure per patient during 2009–2011 (CNY) Statisticsa P
Overall 38,666 (38,178–39,155)    45,319 (44,425–46,213)   
Region   649.44 <0.001   306.1 <0.001
 Eastern 41,943 (41,202–42,684)    47,213 (46,021–48,406)   
 Central 40,410 (39,646–41,173)    52,765 (51,100–54,430)   
 Western 30,234 (29,200–31,269)    32,555 (30,585–34,526)   
Hospital type −6.75 <0.001   −1.20 0.228
 General hospital 36,684 (35,663–37,704)    45,706 (43,883–47,529)   
 Specialized hospital 39,256 (38,700–39,812)    45,182 (44,157–46,207)   
Hospital level 25.60 <0.001   13.26 <0.001
 3A 40,134 (39,625–40,643)    46,751 (45,824–47,677)   
 3A less 22,052 (20,621–23,483)    26,409 (23,612–29,206)   
Number of clinical visits per patient 889.53 <0.001   204.28 < 0.001
 1 29,089 (28,651–29,528)    34,858 (33,981–35,735)   
 2 46,633 (45,530–47,737)    53,959 (52,002–55,917)   
 3 59,441 (57,524–61,357)    60,407 (57,497–63,317)   
 4+ 68,928 (66,774–71,082)    69,055 (65,749–72,360)   
Gender 5.64 <0.001   1.84 0.066
 Male 39,521 (38,961–40,082)    46,046 (45,017–47,074)   
 Female 35,585 (34,605–36,564)    42,768 (40,976–44,561)   
Age at diagnosis (years) 8.65 <0.001   14.42 <0.001
 <45 37,796 (35,539–40,054)    49,384 (43,380–55,388)   
 45–54 39,237 (38,172–40,302)    50,732 (48,367–53,096)   
 55–64 39,588 (38,792–40,384)    46,572 (45,139–48,006)   
 ≥65 37,452 (36,647–38,257)    41,741 (40,426–43,057)   
Pathologic type 23.95 <0.001   11.61 <0.001
 Squamous cell carcinoma 40,711 (40,173–41,250)    48,242 (47,233–49,250)   
 Others 30,216 (29,032–31,399)    35,576 (33,636–37,516)   
Clinical stage 55.51 <0.001   21.80 <0.001
 I 34,460 (32,902–36,017)    40,000 (36,878–43,122)   
 II 39,302 (38,526–40,079)    47,978 (46,381–49,575)   
 III 40,353 (39,491–41,214)    44,962 (43,616–46,309)   
 IV 37,432 (36,180–38,685)    42,972 (40,749–45,194)   
Type of therapy   758.66 <0.001   270.53 <0.001
 Surgery 38,492 (37,890–39,094)    47,778 (46,548–49,008)   
 Surgery and chemotherapy 51,503 (50,316–52,691)    63,843 (61,535–66,151)   
 Radiotherapy 27,933 (26,787–29,079)    29,085 (27,471–30,699)   
 Chemotherapy 27,805 (26,310–29,299)    35,671 (33,121–38,222)   
 Radiotherapy and chemotherapy 53,907 (51,867–55,946)    57,234 (53,865–60,603)   
 Surgery and radiotherapy 57,725 (55,041–60,409)    62,438 (58,708–66,167)   
 Palliative care 13,846 (12,626–15,067)    15,627 (13,187–18,067)   
 Others 23,057 (20,564–25,550)    21,821 (18,386–25,256)   
  1. All expenditure data are presented as mean with 95% confidence interval in parentheses
  2. CNY Chinese Yuan
  3. aThe two-sample Student t test after logarithm transition was used for binary classification variables, including hospital type, hospital level, gender, and pathologic type. The ANOVA test after logarithm transition was used for other multiple categorical variables, including region, number of clinical visits per patient, age at diagnosis, and clinical stage