Table 1 Demographics and clinical characteristics of patients with cancer-related pain who were treated with controlled-release oxycodone/naloxone (OXN-CR) or controlled-release oxycodone (OX-CR) (full analysis set, FAS)
Variable | OXN-CR | OX-CR | P value |
|---|---|---|---|
Total (cases) | 58 | 59 | |
Age, years [cases (%)] | 0.297 | ||
≥70 | 17 (29.3) | 11 (18.6) | |
<70 | 41 (70.7) | 48 (81.4) | |
Sex [cases (%)] | 0.343 | ||
Male | 43 (74.1) | 39 (66.1) | |
Female | 15 (25.9) | 20 (33.9) | |
Cancer type [cases (%)]a | NA | ||
Colorectal | 24 (41.4) | 23 (39.0) | |
Gastric | 10 (17.2) | 8 (13.6) | |
Lung | 6 (10.3) | 5 (8.5) | |
Pancreatic/hepatic bile duct | 6 (10.3) | 9 (15.3) | |
Prostate | 2 (3.4) | 3 (5.1) | |
Esophageal | 3 (5.2) | 1 (1.7) | |
Others | 8 (13.8) | 11 (18.6) | |
Metastasis [cases (%)] | 0.990 | ||
Yes | 57 (98.3) | 58 (98.3) | |
No | 1 (1.7) | 1 (1.7) | |
Prior analgesic use (number of times of administration)b | NA | ||
Strong opioids | 23 | 22 | |
Weak opioids | 39 | 39 | |
NSAID/acetaminophen | 11 | 12 | |
Adjuvant analgesicsc | 1 | 0 | |
Other medicationsd | 1 | 0 | |