Table 3 Prognostic markers involved in suppressing growth of ESCC as reported in original studies
From: Immunohistochemical prognostic markers of esophageal squamous cell carcinoma: a systematic review
Marker | References | Sample size | Clinical stage | OS | DFS | Analytic methods | ||||
|---|---|---|---|---|---|---|---|---|---|---|
HR | 95% CI | P value | HR | 95% CI | P value | |||||
Rb | Mathew et al. [11] | 50 | I–IV | – | – | >0.05 | – | – | – | Log-rank test |
Takeuchi et al. [44] | 90 | I–III | 0.218 | – | 0.11 | – | – | – | Log-rank test | |
Guner et al. [45] | 53 | I–IV | 0.588 | 0.255–1.344 | 0.207 | – | – | – | Cox proportional hazards model (univariate) | |
Ikeguchi et al. [47] | 191 | I–IV | 0.730 | 0.472–1.126 | 0.155 | – | – | – | Cox proportional hazards model | |
Ikeguchi et al. [48] | 107 | I–IV | – | – | – | 0.769 | 0.471–1.222 | 0.257 | Cox proportional hazards model | |
Nam et al. [49] | 51 | I–IV | – | – | >0.05 | – | – | – | Log-rank test | |
Nita et al. [50] | 62 | I–III | – | – | 0.6811 | – | – | – | Log-rank test | |
Wang et al. [51] | 100 | I–IV | – | – | >0.05 | – | – | – | Log-rank test | |
P53 | Okamoto et al. [20] | 86 | I–IV | – | – | 0.30 | – | – | 0.55 | Log-rank test |
Shang et al. [30] | 590 | I–III | 1.556 | 1.063–2.277 | 0.0229 | – | – | – | Cox proportional hazards model | |
Huang et al. [52] | 106 | I–IV | 0.732 | 0.531–1.010 | 0.060 | – | – | – | Cox proportional hazards model | |
Murata et al. [53] | 266 | I–IV | – | – | 0.62 | – | – | 0.73 | Log-rank test | |
Wang et al. [54] | 114 | II–III | 0.800 | 0.254–3.182 | 0.597 | – | – | – | Cox proportional hazards model | |