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Table 4 Univariate and multivariate analysis of prognostic factors for PFS and OS in patients with ENKTL

From: Prognostic role of ABO blood type in patients with extranodal natural killer/T cell lymphoma, nasal type: a triple-center study

Variable PFS OS
Univariate analysis Multivariate analysis Univariate analysis Multivariate analysis
P RR (95% CI) P P RR (95% CI) P
Age (>60 years vs. ≤60 years) 0.002 1.140 (0.886–1.467) 0.308 <0.001 1.904 (1.434–2.527) <0.001
B symptoms (yes vs. no) 0.052 0.019 1.285 (0.981–1.685) 0.069
Tumor size ≥5 cm (yes vs. no) <0.001 1.555 (1.130–2.139) 0.007 <0.001 1.720 (1.233–2.400) 0.001
Extranodal sites ≥2 (yes vs. no) <0.001 0.974 (0.577–1.642) 0.920 <0.001 0.857 (0.491–1.496) 0.586
Regional LN involvement (yes vs. no) <0.001 1.323 (1.041–1.680) 0.022 0.030 1.230 (0.898–1.686) 0.197
Stage III/IV (yes vs. no) <0.001 1.142 (0.650–2.009) 0.644 <0.001 2.114 (1.554–2.875) <0.001
LDH >245 U/L (yes vs. no) <0.001 1.293 (0.937–1.783) 0.118 <0.001 1.514 (1.183–1.936) 0.001
Blood group non-O (yes vs. no) <0.001 1.539 (1.266–1.932) <0.001 0.001 1.491 (1.166–1.906) 0.001
IPI score ≥2 (yes vs. no) <0.001 2.285 (1.751–2.983) <0.001 <0.001 1.021 (0.570–1.828) 0.945
KPI score ≥2 (yes vs. no) <0.001 0.970 (0.642–1.466) 0.886 <0.001 0.846 (0.539–1.327) 0.467
  1. PFS progression-free survival, OS overall survival, RR relative risk, CI confidence interval, LN lymph node, LDH lactate dehydrogenase, IPI International Prognostic Index, KPI Korean Prognostic Index, not assessed