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Table 3 Clinicopathologic features of 126 patients with neuroendocrine carcinoma of the breast in China

From: Neuroendocrine carcinoma of the breast: a review of 126 cases in China

Characteristic

No. of cases (%)

Age (years)

 <50

26 (20.6)

 50–59

19 (15.1)

 60–69

11 (8.7)

 70–79

7 (5.6)

 Data unstratified

63 (50.0)

Gender

 Female

119 (94.4)

 Male

7 (5.6)

Symptom

 Breast lump

124 (98.4)

 Bloody nipple discharge

6 (4.8)

 Nipple erosion

1 (0.8)

 Dimple sign

1 (0.8)

 Skin ulceration

1 (0.8)

Diagnostic examination

 Biopsy before surgery

25 (19.8)

 Breast ultrasound

85 (67.5)

 Mammography

66 (52.4)

 Breast MRI

1 (0.8)

 Chest X-ray

39 (31.0)

Whole body check

 Abdominal ultrasound

60 (47.6)

 Abdominal CT

1 (0.8)

 Chest CT

1 (0.8)

 Pelvic ultrasound

7 (5.6)

 PET/CT

1 (0.8)

Histology

 Well-differentiated (non-small cell)

52 (41.3)

 Poorly-differentiated (small cell)

26 (20.6)

 NM

48 (38.1)

T category

 T1

29 (23.0)

 T2

39 (31.0)

 T3

24 (19.0)

 T4

8 (6.3)

 NM

26 (20.6)

N category

 N0

49 (38.9)

 N1

12 (9.5)

 N2

6 (4.8)

 N3

1 (0.8)

 NM

58 (46.0)

M category

 M0

122 (96.8)

 M1

4 (3.2)

TNM stage

 I

30 (23.8)

 II

60 (47.6)

 III

14 (11.1)

 IV

4 (3.2)

 NM

18 (14.3)

Estrogen receptor status

 Positive

102 (81.0)

 Negative

23 (18.2)

 NM

1 (0.8)

Progesterone receptor status

 Positive

91 (72.2)

 Negative

34 (27.0)

 NM

1 (0.8)

HER2 status

 Overexpressed

19 (15.1)

 Not overexpressed

104 (82.5)

 NM

3 (2.4)

  1. MRI magnetic resonance imaging, CT computed tomography, PET positron emission tomography, HER human epidermal growth factor receptor, NM not mentioned