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Table 2 Clinicopathologic features of seven patients with neuroendocrine carcinoma of the breast

From: Neuroendocrine carcinoma of the breast: a review of 126 cases in China

No.

Age (years)

Sex

Symptom

Histology

TNM stage

Intrinsic subtype

Treatment

Follow-up outcome

1

49

F

Breast lump

Well-differentiated

T2N0M0, IIA

ER3+PR2+HER2−

Surgery, chemotherapy, and endocrine therapy

Alive without tumor

2

78

F

Breast lump

Well-differentiated

T1N0M0, IA

ER3+PR3+HER2−

Surgery, chemotherapy, and endocrine therapy

Died of other causes

3

49

F

Breast lump

Poorly-differentiated

T2N0M0, IIA

ER3+PR+HER2−

Surgery, chemotherapy, and endocrine therapy

Alive without tumor

4

58

F

Breast lump

Well-differentiated

T2N1M0, IIB

ER2+PR2+HER2−

Surgery, chemotherapy, and endocrine therapy

Alive without tumor

5

43

F

Breast lump and skin ulceration

Well-differentiated

T3N2M0, IIIA

ER−PR−HER2−

Surgery and chemotherapy

Alive without tumor

6

60

M

Breast lump

Poorly-differentiated

T4N0M1, IV

ER−PR−HER2−

Chemotherapy

Lost to follow-up

7

33

F

Breast lump

Well-differentiated

T2N1M0, IIB

ER3+PR2+HER2−

Surgery, chemotherapy, and endocrine therapy

Alive without tumor

  1. These patients were diagnosed and treated at the National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, China
  2. F female, M male, ER estrogen receptor, PR progesterone receptor, HER2 human epidermal growth factor receptor 2