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Fig. 2 | Chinese Journal of Cancer

Fig. 2

From: Down-regulation of E-cadherin enhances prostate cancer chemoresistance via Notch signaling

Fig. 2

Chemoresistant PCa cells show enhanced migration and invasion abilities in vitro. a Migratory abilities of PC3, DU145, PC3-TxR, and DU145-TxR cells were determined using transwell assay. b Invasive abilities were determined using transwell assay. On each filter, five microscopic fields (at 200× magnification) were observed, and cells were counted. c Migratory abilities of DU145 and DU145-TxR cells were determined using wound healing assay. Wounded monolayers of DU145 and DU145-TxR cells were photographed 0, 12, and 24 h after the mechanical scratch, and the widths of the wounds were measured in 3-independent wound sites per group. Wound repair was calculated. The mean ± SEM values of data from three independent experiments are presented. *P < 0.05, **P < 0.01

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