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Table 1 Baseline characteristics of all enrolled patients with locally advanced breast cancer

From: Weekly taxane–anthracycline combination regimen versus tri-weekly anthracycline-based regimen for the treatment of locally advanced breast cancer: a randomized controlled trial

Characteristic

FEC arm [cases (%)]

PE arm [cases (%)]

P value

Total

151

142

 

Age (years)

0.430

 ≤35

5 (3.31)

8 (5.63)

 

 >35

146 (96.69)

134 (94.37)

 

Menopausal status

0.263

 Premenopausal

31 (20.53)

22 (15.49)

 

 Postmenopausal

120 (79.47)

120 (84.51)

 

Clinical tumor stage

0.075

 T2

106 (70.20)

86 (60.56)

 

 T3

43 (28.48)

52 (36.62)

 

 T4

2 (1.32)

4 (2.82)

 

Clinical nodal status

0.497

 Involved

130 (86.09)

126 (88.73)

 

 Not involved

21 (13.91)

16 (11.27)

 

ER/PR status

0.533

 Positive

96 (63.58)

89 (62.68)

 

 Negative

47 (31.13)

52 (36.62)

 

 Missing

8 (5.30)

1 (0.70)

 

HER2 (IHC staining)

0.189

 0/1+

64 (42.38)

66 (46.48)

 

 2+

31 (20.53)

26 (18.31)

 

 3+

45 (29.80)

47 (33.10)

 

Missing

11 (7.28)

3 (2.11)

 
  1. PE weekly paclitaxel–epirubicin regimen, FEC tri-weekly 5-fluorouracil–epirubicin–cyclophosphamide regimen, ER estrogen receptor, PR progesterone receptor, HER2 epidermal growth factor receptor-2, IHC immunohistochemistry