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Table 5 Univariate and multivariate analyses of prognostic factors for recurrence-free survival

From: Microwave ablation is as effective as radiofrequency ablation for very-early-stage hepatocellular carcinoma

Variable

Univariate analysis

Multivariate analysis

P value

Odds ratio (95% CI)

P value

Sex: men vs. women

0.617

  

Age (years): >65 vs. ≤65

0.889

  

Heredity: yes vs. no

0.553

  

Etiology: cryptogenic vs. HBV vs. HCV vs. schistosomiasis

0.414

  

Tumor location: favorable vs. unfavorable

0.177

  

Child–Pugh class: A vs. B

0.029

0.787 (0.521–1.190)

0.256

HBV-DNA: positive vs. negative vs. absence

0.086

  

Antiviral therapy: yes vs. no

0.179

  

ALT (U/L): <40 vs. 40–80 vs. >80

0.117

  

TBIL (μmol/L): ≤20 vs. >20

0.117

  

DBIL (μmol/L): ≤7 vs. >7

0.022

1.237 (0.939–1.629)

0.130

ALB (g/L): <35 vs. ≥35

0.105

  

GGT (U/L): <50 vs. 50–100 vs. >100

0.268

  

PLT (×109/L): <100 vs. ≥100

0.073

  

PT (s): ≤13 vs. >13

0.157

  

AFP level (μg/L): <20 vs. 20–200 vs. >200

<0.001

1.370 (1.178–1.593)

<0.001

CA19-9 (kU/L): ≤39 vs. >39

0.772

  

TA modality: MWA vs. RFA

0.309

  

Initial local efficiency: complete vs. incomplete ablation

0.429

  
  1. CI confidence interval, HBV hepatitis B virus, HCV hepatitis C virus, ALT alanine aminotransferase, TBIL total bilirubin, DBIL direct bilirubin, ALB albumin, GGT gamma-glutamyl transpeptidase, PLT platelet, PT prothrombin time, AFP alpha fetoprotein, TA thermal ablation, RFA radiofrequency ablation, MWA microwave ablation