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Table 5 Univariate and multivariate analyses of prognostic factors for recurrence-free survival

From: Microwave ablation is as effective as radiofrequency ablation for very-early-stage hepatocellular carcinoma

Variable Univariate analysis Multivariate analysis
P value Odds ratio (95% CI) P value
Sex: men vs. women 0.617   
Age (years): >65 vs. ≤65 0.889   
Heredity: yes vs. no 0.553   
Etiology: cryptogenic vs. HBV vs. HCV vs. schistosomiasis 0.414   
Tumor location: favorable vs. unfavorable 0.177   
Child–Pugh class: A vs. B 0.029 0.787 (0.521–1.190) 0.256
HBV-DNA: positive vs. negative vs. absence 0.086   
Antiviral therapy: yes vs. no 0.179   
ALT (U/L): <40 vs. 40–80 vs. >80 0.117   
TBIL (μmol/L): ≤20 vs. >20 0.117   
DBIL (μmol/L): ≤7 vs. >7 0.022 1.237 (0.939–1.629) 0.130
ALB (g/L): <35 vs. ≥35 0.105   
GGT (U/L): <50 vs. 50–100 vs. >100 0.268   
PLT (×109/L): <100 vs. ≥100 0.073   
PT (s): ≤13 vs. >13 0.157   
AFP level (μg/L): <20 vs. 20–200 vs. >200 <0.001 1.370 (1.178–1.593) <0.001
CA19-9 (kU/L): ≤39 vs. >39 0.772   
TA modality: MWA vs. RFA 0.309   
Initial local efficiency: complete vs. incomplete ablation 0.429   
  1. CI confidence interval, HBV hepatitis B virus, HCV hepatitis C virus, ALT alanine aminotransferase, TBIL total bilirubin, DBIL direct bilirubin, ALB albumin, GGT gamma-glutamyl transpeptidase, PLT platelet, PT prothrombin time, AFP alpha fetoprotein, TA thermal ablation, RFA radiofrequency ablation, MWA microwave ablation