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Table 4 Univariate and multivariate analyses of prognostic factors for overall survival
| Variable | Univariate analysis | Multivariate analysis | |
|---|---|---|---|
| P value | Odds ratio (95% CI) | P value | |
| Sex: men vs. women | 0.222 | ||
| Age (years): >65 vs. ≤65 | 0.762 | ||
| Heredity: yes vs. no | 0.932 | ||
| Etiology: cryptogenic vs. HBV vs. HCV vs. schistosomiasis | 0.211 | ||
| Tumor location: favorable vs. unfavorable | 0.294 | ||
| Child–Pugh class: A vs. B | 0.083 | ||
| HBV-DNA: positive vs. negative vs. absence | 0.839 | ||
| Antiviral therapy: yes vs. no | 0.002 | 0.468 (0.299–0.734) | 0.001 |
| ALT (U/L): <40 vs. 40–80 vs. >80 | 0.556 | ||
| TBIL (μmol/L): ≤20 vs. >20 | 0.563 | ||
| DBIL (μmol/L): ≤7 vs. >7 | 0.079 | ||
| ALB (g/L): <35 vs. ≥35 | 0.036 | 1.200 (0.687–2.095) | 0.521 |
| GGT (U/L): <50 vs. 50–100 vs. >100 | 0.366 | ||
| PLT (×109/L): <100 vs. ≥100 | 0.199 | ||
| PT (s): ≤13 vs. >13 | 0.115 | ||
| AFP level (μg/L): <20 vs. 20–200 vs. >200 | 0.014 | 0.881 (0.679–1.143) | 0.341 |
| CA19-9 (kU/L): ≤39 vs. >39 | 0.878 | ||
| TA modality: MWA vs. RFA | 0.331 | ||
| Initial local efficiency: complete vs. incomplete ablation | 0.182 | ||
| LTP: presence vs. absence | <0.001 | 3.711 (2.410–5.714) | <0.001 |
| DR: presence vs. absence | 0.152 | ||
| Treatment of recurrence: radical vs. palliative | <0.001 | 0.241 (0.147–0.395) | <0.001 |
