Microwave ablation is as effective as radiofrequency ablation for very-early-stage hepatocellular carcinoma

Cancer Communications

Table 4 Univariate and multivariate analyses of prognostic factors for overall survival

Variable	Univariate analysis	Multivariate analysis
Variable	P value	Odds ratio (95% CI)	P value
Sex: men vs. women	0.222
Age (years): >65 vs. ≤65	0.762
Heredity: yes vs. no	0.932
Etiology: cryptogenic vs. HBV vs. HCV vs. schistosomiasis	0.211
Tumor location: favorable vs. unfavorable	0.294
Child–Pugh class: A vs. B	0.083
HBV-DNA: positive vs. negative vs. absence	0.839
Antiviral therapy: yes vs. no	0.002	0.468 (0.299–0.734)	0.001
ALT (U/L): <40 vs. 40–80 vs. >80	0.556
TBIL (μmol/L): ≤20 vs. >20	0.563
DBIL (μmol/L): ≤7 vs. >7	0.079
ALB (g/L): <35 vs. ≥35	0.036	1.200 (0.687–2.095)	0.521
GGT (U/L): <50 vs. 50–100 vs. >100	0.366
PLT (×10⁹/L): <100 vs. ≥100	0.199
PT (s): ≤13 vs. >13	0.115
AFP level (μg/L): <20 vs. 20–200 vs. >200	0.014	0.881 (0.679–1.143)	0.341
CA19-9 (kU/L): ≤39 vs. >39	0.878
TA modality: MWA vs. RFA	0.331
Initial local efficiency: complete vs. incomplete ablation	0.182
LTP: presence vs. absence	<0.001	3.711 (2.410–5.714)	<0.001
DR: presence vs. absence	0.152
Treatment of recurrence: radical vs. palliative	<0.001	0.241 (0.147–0.395)	<0.001

CI confidence interval, HBV hepatitis B virus, HCV hepatitis C virus, ALT alanine aminotransferase, TBIL total bilirubin, DBIL direct bilirubin, ALB albumin, GGT gamma-glutamyl transpeptidase, PLT platelet, PT prothrombin time, AFP alpha fetoprotein, TA thermal ablation, RFA radiofrequency ablation, MWA microwave ablation, LTP local tumor progression, DR distant recurrence

ISSN: 2523-3548