Skip to main content

Table 4 The number and percentages of intrasplenic and hepatic tumor formation after intrasplenic injection of HCT116 stable cell lines (1×106 cells each) for 8 weeks

From: The loss-of-function mutations and down-regulated expression of ASB3 gene promote the growth and metastasis of colorectal cancer cells

Modified HCT116 stable cell line

Number of mice

Tumor formationa

Intrasplenic

Liver

Vectro

8

6 (75.0)

6 (75.0)

ΔSOCS

8

6 (75.0)

6 (75.0)

WT ASB3

8

4 (50.0)

2 (25.0)*

G135E

8

7 (87.5)

8 (100)

K339I

8

7 (87.5)

8 (100)

G135E/K339I

8

8 (100)

8 (100)

  1. * P < 0.05 compared with other groups (Students’ t test)
  2. a The data are presented as the number of mice with tumors followed by percentage in parentheses
Back to article page

Cancer Communications

ISSN: 2523-3548

Contact us