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Table 1 Thirty-seven single nucleotide polymorphisms (SNPs) in DNA mismatch repair (MMR) genes

From: Association between DNA mismatch repair gene polymorphisms and platinum-based chemotherapy toxicity in non-small cell lung cancer patients

Gene SNP (rs number) Allele Localization Call rate (%) MAF HWE
MLH1 rs10849 G/A 3′-UTR 99.55 0.09 0.764
rs1540354 A/T Intron 97.73 0.68 0.635
rs749072 T/C Intron 97.73 0.62 0.217
MSH2 rs10191478 T/G Intron 97.73 0.20 0.264
rs12999145 A/G Intron 98.64 0.53 0.783
rs13019654 G/T Intron 96.82 0.28 0.710
rs1981929 G/A Intron 97.27 0.86 0.309
rs2303428 A/C Intron 98.64 0.33 0.234
rs4608577 T/G Intron 93.18 0.13 0.106
rs4952887 C/T Intron 98.18 0.15 0.124
rs6544991 A/C Intron 95.00 0.36 0.605
rs7602094 T/C Intron 95.91 0.66 0.560
MSH3 rs245340 A/C Intron 97.73 0.24 0.203
rs245346 T/C Intron 97.73 0.45 0.738
rs26778 A/T Intron 96.36 0.59 0.713
rs26784 T/C Intron 97.73 0.37 0.860
rs3816729 A/G Intron 96.36 0.30 0.927
rs6151627 A/G Intron 99.09 0.29 0.554
rs6151670 C/G Intron 98.18 0.28 0.258
rs6151892 T/A Intron 99.09 0.33 0.729
rs6151914 C/T Intron 97.73 0.09 0.065
rs7709909 C/T Intron 99.09 0.31 0.572
MSH4 rs3806162 T/G 5′ near gene 99.09 0.22 0.393
rs5745532 T/C Intron 99.09 0.75 0.112
MSH5 rs3117572 G/A Intron 98.64 0.28 0.103
rs409558 A/G Intron 100.00 0.13 0.312
rs707937 C/G Intron 96.82 0.42 0.369
rs707938 A/G Synonymous 97.27 0.30 0.428
rs707939 G/T Intron 100.00 0.39 0.097
rs805304 C/A 5′ near gene 98.18 0.69 0.448
MSH6 rs2020910 T/A Intron 99.09 0.17 0.893
rs2348244 T/C Intron 99.09 0.39 0.856
rs2710163 T/C Intron 98.18 0.70 0.856
rs3136329 T/C Intron 97.27 0.13 0.108
rs3732190 G/A Intron 95.91 0.09 0.933
rs6713506 G/A Intron 98.64 0.06 0.852
rs6742522 G/A Intron 99.09 0.11 0.259
  1. MLH1 MutL homolog 1, MSH2-6 MutS homolog 2-6, A adenine, T thymine, C cytosine, G guanine, UTR untranslated region, MAF minor allele frequency, HWE Hardy–Weinberg equilibrium