Table 1 The baseline clinicopathologic characteristics of underweight, normal weight, overweight, and obese patients with stage I NSCLC, stratified by BMI
From: Effect of body mass index on survival of patients with stage I non-small cell lung cancer
Characteristic | Overall (cases) | Underweight [cases (%)] | Normal weight [cases (%)] | Overweight [cases (%)] | Obese [cases (%)] | P value |
|---|---|---|---|---|---|---|
Total | 624 | 44 | 245 | 306 | 29 | |
Gender | 0.668 | |||||
Male | 408 (65.4) | 26 (13.6) | 166 (67.8) | 198 (64.7) | 18 (62.1) | |
Female | 216 (34.6) | 18 (86.4) | 79 (32.2) | 108 (35.3) | 11 (37.9) | |
Age (years) | 0.991 | |||||
<60 | 285 (45.7) | 20 (2.3) | 114 (46.5) | 138 (45.1) | 13 (44.8) | |
≥60 | 339 (54.3) | 24 (97.7) | 131 (53.5) | 168 (54.9) | 16 (55.2) | |
Smoking | 0.001 | |||||
Never | 318 (51.0) | 23 (4.5) | 101 (41.2) | 178 (58.2) | 16 (55.2) | |
Current or ever | 306 (49.0) | 21 (95.5) | 144 (58.8) | 128 (41.8) | 13 (44.8) | |
Hypertension | <0.001 | |||||
With | 150 (24.0) | 6 (13.6) | 38 (15.5) | 93 (30.4) | 13 (44.8) | |
Without | 474 (76.0) | 38 (86.4) | 207 (84.5) | 213 (69.6) | 16 (55.2) | |
Diabetes | 0.318 | |||||
With | 46 (7.4) | 1 (2.3) | 18 (7.3) | 23 (7.5) | 4 (13.8) | |
Without | 578 (92.6) | 43 (97.7) | 227 (92.7) | 283 (92.5) | 25 (86.2) | |
Heart disease | 0.482 | |||||
With | 18 (2.9) | 2 (4.5) | 7 (2.9) | 7 (2.3) | 2 (6.9) | |
Without | 606 (97.1) | 42 (95.5) | 238 (97.1) | 299 (97.7) | 27 (93.1) | |
FEV1/FVC (%) | 0.011 | |||||
<70 | 83 (13.3) | 11 (25.0) | 40 (16.3) | 30 (9.8) | 2 (6.9) | |
≥70 | 541 (86.7) | 33 (75.0) | 205 (83.7) | 276 (90.2) | 27 (93.1) | |
Type of surgery | 0.979 | |||||
Open thoracotomy | 537 (86.1) | 37 (84.1) | 210 (85.7) | 264 (86.3) | 25 (86.2) | |
VATS | 87 (13.9) | 7 (15.9) | 35 (14.3) | 42(13.7) | 4 (13.8) | |
Extent of resection | 0.681 | |||||
Lobectomy or bilobectomy | 611 (97.9) | 44 (100.0) | 239 (97.6) | 299 (97.7) | 29 (100.0) | |
Pneumonectomy | 13 (2.1) | 0 (0.0) | 6 (2.4) | 7 (2.3) | 0 (0.0) | |
Adjuvant chemotherapy | 0.967 | |||||
Absent | 486 (77.9) | 34 (77.3) | 193 (78.8) | 236 (77.1) | 23 (79.3) | |
Present | 138 (22.1) | 10 (22.7) | 52 (21.2) | 70 (22.9) | 6 (20.7) | |
Histological type | 0.432 | |||||
Adenocarcinoma | 406 (65.1) | 29 (65.9) | 152 (62.0) | 203 (66.3) | 22 (75.9) | |
Squamous cell carcinoma | 140 (22.4) | 12 (27.3) | 62 (25.3) | 63 (20.6) | 3 (10.3) | |
Other NSCLC | 78 (12.5) | 3 (6.8) | 31 (12.7) | 40 (13.1) | 4 (13.8) | |
Histologic differentiation | 0.131 | |||||
Poor | 212 (34.0) | 17 (38.6) | 94 (38.4) | 92 (30.1) | 9 (31.0) | |
Moderate | 300 (48.1) | 17 (38.6) | 113 (46.1) | 159 (52.0) | 11 (37.9) | |
Well | 112 (17.9) | 10 (22.7) | 38 (15.5) | 55 (18.0) | 9 (31.0) | |
Visceral pleural invasion | 0.005 | |||||
Absent | 408 (65.4) | 32 (72.7) | 140 (57.1) | 212 (69.3) | 23 (79.3) | |
Present | 216 (34.6) | 12 (27.3) | 105 (42.9) | 94 (30.7) | 6 (20.7) | |
T stage | <0.001 | |||||
T1a | 132 (21.2) | 10 (22.7) | 36 (14.7) | 78 (25.5) | 8 (27.6) | |
T1b | 113 (18.1) | 13 (29.5) | 31 (12.7) | 59 (19.3) | 9 (31.0) | |
T2a | 379 (60.7) | 21 (47.7) | 178 (72.7) | 169 (55.2) | 12 (41.4) | |
Clinical TNM stage | <0.001 | |||||
IA | 245 (39.3) | 23 (52.3) | 67 (27.3) | 137 (44.8) | 17 (58.6) | |
IB | 379 (60.7) | 21 (47.7) | 178 (72.7) | 169 (55.2) | 12 (41.4) |